Dendritic cell-based therapy: A review focusing on antigenic selection

R. M. Syme, T. L. Bryan, S. Glück

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Recently, technologies have developed that allow for the culturing of antigen-presenting cells (APC), such as dendritic cells (DC). The normal function of these cells is to present antigens to T cells, which then specifically recognize and ultimately eliminate the antigen source. Over the past number of years, these cells have been used in a variety of different immunotherapeutic strategies. Paramount in the success of such endeavors is the generation of desired T cell responses through the selection of appropriate antigens. This paper will serve to discuss the development and current status of dendritic cell-based therapy focusing on antigen selection for cancer.

Original languageEnglish (US)
Pages (from-to)601-608
Number of pages8
JournalJournal of Hematotherapy and Stem Cell Research
Volume10
Issue number5
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Immunology
  • Hematology

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