Dementia with bilateral medial temporal lobe ischemia

Bruce T. Volpe; Carol K. Petito

doi:10.1212/wnl.35.12.1793

Dementia with bilateral medial temporal lobe ischemia

Bruce T. Volpe, Carol K. Petito

Pathology

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

Neuropathologic examination of two patients with dementia showed chronic bilateral medial temporal lobe ischemic damage that included the hippocampus (particularly the CA-1 region), subiculum, and amygdala. Both patients had several myocardial infarctions, and the relatively circumscribed cerebral injury may have resulted from one or more episodes of global hypoxic ischemia. Focal hippocampal injury has been associated with amnesia. The additional damage to medial temporal lobe structures may have caused the dementia.

Original language	English (US)
Pages (from-to)	1793-1797
Number of pages	5
Journal	Neurology
Volume	35
Issue number	12
DOIs	https://doi.org/10.1212/wnl.35.12.1793
State	Published - Dec 1985

ASJC Scopus subject areas

Clinical Neurology

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Dementia with bilateral medial temporal lobe ischemia

Abstract

ASJC Scopus subject areas

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