Delayed-Enhancement Cardiovascular Magnetic Resonance Coronary Artery Wall Imaging. Comparison With Multislice Computed Tomography and Quantitative Coronary Angiography

Susan B. Yeon, Adeel Sabir, Melvin Clouse, Pedro O. Martinezclark, Dana C. Peters, Thomas H. Hauser, C. Michael Gibson, Reza Nezafat, David Maintz, Warren J. Manning, René M. Botnar

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Abstract

Objectives: We examined whether delayed-enhancement cardiovascular magnetic resonance (DE-CMR) coronary artery wall imaging correlated with atherosclerosis detected by using multislice computed tomography (MSCT) and quantitative coronary angiography (QCA). Background: The use of DE-CMR coronary vessel wall imaging may provide a noninvasive method to assess diseased coronary vessel walls. Methods: We performed DE-CMR coronary artery wall imaging in 14 patients with cardiovascular risk factors and 6 healthy subjects without risk factors. Results: A greater prevalence of strong DE was noted with greater MSCT evidence of disease, with DE in 2 (7%) of 30 coronary segments with no plaque by MSCT, in 1 (10%) of 10 segments with noncalcified plaque on MSCT, and in 16 (36%) of 44 segments with calcifications by MSCT (p = 0.009, adjusted p = 0.035). Delayed enhancement was observed in 8 (53%) of 15 segments with >20% coronary artery stenosis by QCA but also in 12 (15%) of 80 segments without angiographically apparent coronary disease (p = 0.004, adjusted p = 0.01). Conclusions: The use of DE-CMR allowed us to identify areas of DE that correlate with severity of atherosclerosis by MSCT and QCA. This novel approach may be useful for the assessment of coronary vessel wall in patients with suspected coronary artery disease.

Original languageEnglish
Pages (from-to)441-447
Number of pages7
JournalJournal of the American College of Cardiology
Volume50
Issue number5
DOIs
StatePublished - Jul 31 2007

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Multidetector Computed Tomography
Coronary Angiography
Coronary Vessels
Magnetic Resonance Spectroscopy
Atherosclerosis
Coronary Stenosis
Coronary Disease
Coronary Artery Disease
Healthy Volunteers

ASJC Scopus subject areas

  • Nursing(all)

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Delayed-Enhancement Cardiovascular Magnetic Resonance Coronary Artery Wall Imaging. Comparison With Multislice Computed Tomography and Quantitative Coronary Angiography. / Yeon, Susan B.; Sabir, Adeel; Clouse, Melvin; Martinezclark, Pedro O.; Peters, Dana C.; Hauser, Thomas H.; Gibson, C. Michael; Nezafat, Reza; Maintz, David; Manning, Warren J.; Botnar, René M.

In: Journal of the American College of Cardiology, Vol. 50, No. 5, 31.07.2007, p. 441-447.

Research output: Contribution to journalArticle

Yeon, SB, Sabir, A, Clouse, M, Martinezclark, PO, Peters, DC, Hauser, TH, Gibson, CM, Nezafat, R, Maintz, D, Manning, WJ & Botnar, RM 2007, 'Delayed-Enhancement Cardiovascular Magnetic Resonance Coronary Artery Wall Imaging. Comparison With Multislice Computed Tomography and Quantitative Coronary Angiography', Journal of the American College of Cardiology, vol. 50, no. 5, pp. 441-447. https://doi.org/10.1016/j.jacc.2007.03.052
Yeon, Susan B. ; Sabir, Adeel ; Clouse, Melvin ; Martinezclark, Pedro O. ; Peters, Dana C. ; Hauser, Thomas H. ; Gibson, C. Michael ; Nezafat, Reza ; Maintz, David ; Manning, Warren J. ; Botnar, René M. / Delayed-Enhancement Cardiovascular Magnetic Resonance Coronary Artery Wall Imaging. Comparison With Multislice Computed Tomography and Quantitative Coronary Angiography. In: Journal of the American College of Cardiology. 2007 ; Vol. 50, No. 5. pp. 441-447.
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abstract = "Objectives: We examined whether delayed-enhancement cardiovascular magnetic resonance (DE-CMR) coronary artery wall imaging correlated with atherosclerosis detected by using multislice computed tomography (MSCT) and quantitative coronary angiography (QCA). Background: The use of DE-CMR coronary vessel wall imaging may provide a noninvasive method to assess diseased coronary vessel walls. Methods: We performed DE-CMR coronary artery wall imaging in 14 patients with cardiovascular risk factors and 6 healthy subjects without risk factors. Results: A greater prevalence of strong DE was noted with greater MSCT evidence of disease, with DE in 2 (7{\%}) of 30 coronary segments with no plaque by MSCT, in 1 (10{\%}) of 10 segments with noncalcified plaque on MSCT, and in 16 (36{\%}) of 44 segments with calcifications by MSCT (p = 0.009, adjusted p = 0.035). Delayed enhancement was observed in 8 (53{\%}) of 15 segments with >20{\%} coronary artery stenosis by QCA but also in 12 (15{\%}) of 80 segments without angiographically apparent coronary disease (p = 0.004, adjusted p = 0.01). Conclusions: The use of DE-CMR allowed us to identify areas of DE that correlate with severity of atherosclerosis by MSCT and QCA. This novel approach may be useful for the assessment of coronary vessel wall in patients with suspected coronary artery disease.",
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AU - Sabir, Adeel

AU - Clouse, Melvin

AU - Martinezclark, Pedro O.

AU - Peters, Dana C.

AU - Hauser, Thomas H.

AU - Gibson, C. Michael

AU - Nezafat, Reza

AU - Maintz, David

AU - Manning, Warren J.

AU - Botnar, René M.

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AB - Objectives: We examined whether delayed-enhancement cardiovascular magnetic resonance (DE-CMR) coronary artery wall imaging correlated with atherosclerosis detected by using multislice computed tomography (MSCT) and quantitative coronary angiography (QCA). Background: The use of DE-CMR coronary vessel wall imaging may provide a noninvasive method to assess diseased coronary vessel walls. Methods: We performed DE-CMR coronary artery wall imaging in 14 patients with cardiovascular risk factors and 6 healthy subjects without risk factors. Results: A greater prevalence of strong DE was noted with greater MSCT evidence of disease, with DE in 2 (7%) of 30 coronary segments with no plaque by MSCT, in 1 (10%) of 10 segments with noncalcified plaque on MSCT, and in 16 (36%) of 44 segments with calcifications by MSCT (p = 0.009, adjusted p = 0.035). Delayed enhancement was observed in 8 (53%) of 15 segments with >20% coronary artery stenosis by QCA but also in 12 (15%) of 80 segments without angiographically apparent coronary disease (p = 0.004, adjusted p = 0.01). Conclusions: The use of DE-CMR allowed us to identify areas of DE that correlate with severity of atherosclerosis by MSCT and QCA. This novel approach may be useful for the assessment of coronary vessel wall in patients with suspected coronary artery disease.

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