Defining Treatment Response and Symptom Remission for Anxiety Disorders in Pediatric Autism Spectrum Disorders Using the Pediatric Anxiety Rating Scale

Carly J. Johnco, Alessandro S. De Nadai, Adam B. Lewin, Jill Ehrenreich May, Jeffrey J. Wood, Eric A. Storch

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This study examined optimal guidelines to assess treatment response and remission for anxiety in youth with autism spectrum disorders (ASD) using the Pediatric Anxiety Rating Scale (PARS). Data was collected for 108 children aged 7–16 years with comorbid anxiety and ASD before and after receiving cognitive behavior therapy. Optimal cut-offs on the PARS were assessed using signal detection analyses using receiver operating characteristic methods. Maximum agreement with response criteria was achieved at 15 % reduction in symptoms on the PARS. Maximum agreement with remission criteria was achieved at 40 % reduction in symptoms, or at a score of 10 or below at post-treatment. Results have implications for standardizing criteria used in research trials and clinical practice.

Original languageEnglish (US)
Pages (from-to)3232-3242
Number of pages11
JournalJournal of Autism and Developmental Disorders
Volume45
Issue number10
DOIs
StatePublished - Jun 2 2015

Fingerprint

Anxiety Disorders
Anxiety
Pediatrics
Therapeutics
Cognitive Therapy
ROC Curve
Autism Spectrum Disorder
Clinical Trials
Guidelines
Research

Keywords

  • Autism
  • Children
  • Measurement
  • Pediatric Anxiety Rating Scale
  • Treatment

ASJC Scopus subject areas

  • Developmental and Educational Psychology

Cite this

Defining Treatment Response and Symptom Remission for Anxiety Disorders in Pediatric Autism Spectrum Disorders Using the Pediatric Anxiety Rating Scale. / Johnco, Carly J.; De Nadai, Alessandro S.; Lewin, Adam B.; Ehrenreich May, Jill; Wood, Jeffrey J.; Storch, Eric A.

In: Journal of Autism and Developmental Disorders, Vol. 45, No. 10, 02.06.2015, p. 3232-3242.

Research output: Contribution to journalArticle

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