Deep brain stimulation complicated by bilateral large cystic cavitation around the leads in a patient with Parkinson's disease

Jonathan Jagid, Karthik Madhavan, Neel Desai, Amade Bregy, Mehul Desai, Armando Ruiz, Robert Quencer, Howard Landy

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Deep brain stimulation (DBS) is an approved and effective therapy for patients suffering from advanced Parkinson's disease (PD). Several clinical trials have indicated significant motor function improvement in patients undergoing subthalamic nucleus stimulation. This therapy is, rarely, associated with complications, mostly related to infections, seizures or stimulationinduced side effects. We report a case of a 71-year-old man with a 10-year history of PD who underwent bilateral placement of subthalamic nucleus DBS. As a complication, the patient showed subjective postoperative cognitive decline, and subsequent MRI showed peri-lead oedema, which progressed to large cystic cavitation around the leads without indication of infection. The patient received steroid therapy and the cavitations regressed without surgical intervention.

Original languageEnglish (US)
Article number211470
JournalBMJ Case Reports
StatePublished - Oct 16 2015


ASJC Scopus subject areas

  • Medicine(all)

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