D-Aspartic acid in purified myelin and myelin basic protein

George H. Fisher, Nancy M. Garcia, Iris L. Payan, Rodolfo Cadilla-Perezrios, William A. Sheremata, Eugene H. Man

Research output: Contribution to journalArticlepeer-review

70 Scopus citations


The presence of the biologically uncommon D-isomer of aspartic acid in the white matter of human brains has been reported previously from this laboratory (1). We now report that the level of D-aspartate in human brains is higher in purified myelin than in white matter and is even higher in the myelin basic protein fraction. There also appears to be a difference in the level of D-aspartate found in human brain as compared to bovine brain, possibly a species or age-related difference.

Original languageEnglish (US)
Pages (from-to)683-687
Number of pages5
JournalBiochemical and biophysical research communications
Issue number2
StatePublished - Mar 13 1986

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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