D-Aspartic acid in purified myelin and myelin basic protein

George H. Fisher, Nancy M. Garcia, Iris L. Payan, Rodolfo Cadilla-Perezrios, William A. Sheremata, Eugene H. Man

Research output: Contribution to journalArticle

69 Scopus citations

Abstract

The presence of the biologically uncommon D-isomer of aspartic acid in the white matter of human brains has been reported previously from this laboratory (1). We now report that the level of D-aspartate in human brains is higher in purified myelin than in white matter and is even higher in the myelin basic protein fraction. There also appears to be a difference in the level of D-aspartate found in human brain as compared to bovine brain, possibly a species or age-related difference.

Original languageEnglish (US)
Pages (from-to)683-687
Number of pages5
JournalBiochemical and biophysical research communications
Volume135
Issue number2
DOIs
StatePublished - Mar 13 1986

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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    Fisher, G. H., Garcia, N. M., Payan, I. L., Cadilla-Perezrios, R., Sheremata, W. A., & Man, E. H. (1986). D-Aspartic acid in purified myelin and myelin basic protein. Biochemical and biophysical research communications, 135(2), 683-687. https://doi.org/10.1016/0006-291X(86)90047-1