D-Aspartic acid in purified myelin and myelin basic protein

George H. Fisher, Nancy M. Garcia, Iris L. Payan, Rodolfo Cadilla-Perezrios, William Sheremata, Eugene H. Man

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

The presence of the biologically uncommon D-isomer of aspartic acid in the white matter of human brains has been reported previously from this laboratory (1). We now report that the level of D-aspartate in human brains is higher in purified myelin than in white matter and is even higher in the myelin basic protein fraction. There also appears to be a difference in the level of D-aspartate found in human brain as compared to bovine brain, possibly a species or age-related difference.

Original languageEnglish
Pages (from-to)683-687
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume135
Issue number2
DOIs
StatePublished - Mar 13 1986

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D-Aspartic Acid
Myelin Basic Protein
Myelin Sheath
Brain
Aspartic Acid
Isomers
White Matter

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Fisher, G. H., Garcia, N. M., Payan, I. L., Cadilla-Perezrios, R., Sheremata, W., & Man, E. H. (1986). D-Aspartic acid in purified myelin and myelin basic protein. Biochemical and Biophysical Research Communications, 135(2), 683-687. https://doi.org/10.1016/0006-291X(86)90047-1

D-Aspartic acid in purified myelin and myelin basic protein. / Fisher, George H.; Garcia, Nancy M.; Payan, Iris L.; Cadilla-Perezrios, Rodolfo; Sheremata, William; Man, Eugene H.

In: Biochemical and Biophysical Research Communications, Vol. 135, No. 2, 13.03.1986, p. 683-687.

Research output: Contribution to journalArticle

Fisher, GH, Garcia, NM, Payan, IL, Cadilla-Perezrios, R, Sheremata, W & Man, EH 1986, 'D-Aspartic acid in purified myelin and myelin basic protein', Biochemical and Biophysical Research Communications, vol. 135, no. 2, pp. 683-687. https://doi.org/10.1016/0006-291X(86)90047-1
Fisher GH, Garcia NM, Payan IL, Cadilla-Perezrios R, Sheremata W, Man EH. D-Aspartic acid in purified myelin and myelin basic protein. Biochemical and Biophysical Research Communications. 1986 Mar 13;135(2):683-687. https://doi.org/10.1016/0006-291X(86)90047-1
Fisher, George H. ; Garcia, Nancy M. ; Payan, Iris L. ; Cadilla-Perezrios, Rodolfo ; Sheremata, William ; Man, Eugene H. / D-Aspartic acid in purified myelin and myelin basic protein. In: Biochemical and Biophysical Research Communications. 1986 ; Vol. 135, No. 2. pp. 683-687.
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