Cytoplasmic tubular arrays in cells of American Burkitt's type lymphoma

Nina A. Popoff, Theodore I. Malinin

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Aggregates of tubular arrays associated with cysternae of endoplasmic reticulum were observed in untreated primary American form Burkitt's lymphoma. The tumor occurred in a white female child who died with severe central nervous system (CNS) involvement. Although the significance of the tubular structures and the mechanism by which they are formed remain unknown, the predilection of these structures for lymphoid and reticuloendothelial cells and their frequent association wih either viral or suspected viral conditions cannot be overlooked. However, it is possible that the tubular structures may reflect an increased production of antibody protein in response to a viral antigen.

Original languageEnglish (US)
Pages (from-to)275-284
Number of pages10
JournalCancer
Volume37
Issue number1
DOIs
StatePublished - Jan 1976

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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