Cytoplasmic Inclusions (Cont.)

To the Editor: We read with considerable interest the letter by Zyngier¹ as well as his original article.² The cytoplasmic crystalloid inclusions that he found within lung alveolar cells of mice infected with Toxocara canis are completely different from the nuclear and cytoplasmic fibrillary inclusions described by us in neutrophils trapped in human renal allografts.³⁴ We do not think that they are the morphologic manifestation of the same pathologic process. Crystalloid inclusions similar to those illustrated in his letter have been found within the endoplasmic reticulum of both malignant and reactive plasma cells.^{5 6 7 8} Their biochemical nature has not been. No extract is available for articles shorter than 400 words.