Cytokines. A unifying concept in the pathogenesis of clubbing

G. Yosipovitch; A. Weinberger

doi:10.1016/0306-9877(91)90252-T

Cytokines. A unifying concept in the pathogenesis of clubbing

G. Yosipovitch, A. Weinberger

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Finger clubbing is a striking clinical sign associated with a large variety of diseases and syndromes. Although clubbing is poorly understood, we hypothesise that there is a final common pathway in the pathogenesis of clubbing by which there is increased growth of connective tissue and augmented blood flow mediated or stimulated by cytokines, which are either over-produced or poorly eliminated.

Original language	English (US)
Pages (from-to)	122-125
Number of pages	4
Journal	Medical Hypotheses
Volume	36
Issue number	2
DOIs	https://doi.org/10.1016/0306-9877(91)90252-T
State	Published - Oct 1991
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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abstract = "Finger clubbing is a striking clinical sign associated with a large variety of diseases and syndromes. Although clubbing is poorly understood, we hypothesise that there is a final common pathway in the pathogenesis of clubbing by which there is increased growth of connective tissue and augmented blood flow mediated or stimulated by cytokines, which are either over-produced or poorly eliminated.",

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AB - Finger clubbing is a striking clinical sign associated with a large variety of diseases and syndromes. Although clubbing is poorly understood, we hypothesise that there is a final common pathway in the pathogenesis of clubbing by which there is increased growth of connective tissue and augmented blood flow mediated or stimulated by cytokines, which are either over-produced or poorly eliminated.

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