Cysticidal activity of antifungals against different genotypes of Acanthamoeba

Alfonso Iovieno, Darlene Miller, Dolena R. Ledee, Eduardo C. Alfonso

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Antifungal drugs have been proposed as a novel treatment for Acanthamoeba keratitis. The cysticidal activity of several antifungal compounds was tested against different genotypes of culture collection and clinical isolates of Acanthamoeba. Only voriconazole and posaconazole were found to be cysticidal, with no differences in activity observed between clinical and culture collection isolates.

Original languageEnglish (US)
Pages (from-to)5626-5628
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume58
Issue number9
DOIs
StatePublished - Sep 2014

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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