Cysticidal activity of antifungals against different genotypes of Acanthamoeba

Alfonso Iovieno, Darlene Miller, Dolena R. Ledee, Eduardo C. Alfonso

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Antifungal drugs have been proposed as a novel treatment for Acanthamoeba keratitis. The cysticidal activity of several antifungal compounds was tested against different genotypes of culture collection and clinical isolates of Acanthamoeba. Only voriconazole and posaconazole were found to be cysticidal, with no differences in activity observed between clinical and culture collection isolates.

Original languageEnglish (US)
Pages (from-to)5626-5628
Number of pages3
JournalAntimicrobial agents and chemotherapy
Issue number9
StatePublished - Sep 2014

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases


Dive into the research topics of 'Cysticidal activity of antifungals against different genotypes of Acanthamoeba'. Together they form a unique fingerprint.

Cite this