Cushing's disease: Pituitary imaging

S. Tripathi, A. C. Ammini, Rita Bhatia, R. Gupta, M. Berry, C. Sarkar, H. Mahajan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Fourteen patients with adrenocorticotropic hormone (ACTH)-dependent hypercortisolism underwent pituitary scanning with computed axial tomography (CT) and magnetic resonance imaging (MRI). Computed tomography revealed pituitary macroadenomas in two patients, pituitary hyperplasia in one and a suspicion of pituitary microadenoma in one. Thirteen patients underwent MRI. One with a macroadenoma diagnosed on CT did not undergo MRI. The MRI revealed a pituitary macroadenoma in one, microadenoma in three and hyperplasia in two cases. Magnetic resonance imaging following gadolinium diethylene triamine penta acetic acid (gd-DTPA) enhancement revealed four more pituitary microadenomas. All patients who had pituitary adenomas (micro and macro) and hyperplasia underwent trans-sphenoidal pituitary surgery. One of the two patients, who had an enlarged pituitary on imaging but no demonstrable adenoma, was found to have a microadenoma at surgery. Patients with ACTH- dependent hypercortisolism should undergo MRI of the pituitary gland to identify/localize corticotroph pituitary adenomas. The study should include gd-DTPA enhancement in cases where the scan is normal.

Original languageEnglish
Pages (from-to)183-186
Number of pages4
JournalAustralasian Radiology
Volume38
Issue number3
StatePublished - Jan 1 1994
Externally publishedYes

Fingerprint

Pituitary ACTH Hypersecretion
Magnetic Resonance Imaging
Hyperplasia
Rubiaceae
Cushing Syndrome
Tomography
Gadolinium
Pituitary Neoplasms
Acetic Acid
Adrenocorticotropic Hormone
ACTH-Secreting Pituitary Adenoma
Pituitary Gland
Adenoma

Keywords

  • computed tomography scan
  • Cushing's disease
  • imaging
  • magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Tripathi, S., Ammini, A. C., Bhatia, R., Gupta, R., Berry, M., Sarkar, C., & Mahajan, H. (1994). Cushing's disease: Pituitary imaging. Australasian Radiology, 38(3), 183-186.

Cushing's disease : Pituitary imaging. / Tripathi, S.; Ammini, A. C.; Bhatia, Rita; Gupta, R.; Berry, M.; Sarkar, C.; Mahajan, H.

In: Australasian Radiology, Vol. 38, No. 3, 01.01.1994, p. 183-186.

Research output: Contribution to journalArticle

Tripathi, S, Ammini, AC, Bhatia, R, Gupta, R, Berry, M, Sarkar, C & Mahajan, H 1994, 'Cushing's disease: Pituitary imaging', Australasian Radiology, vol. 38, no. 3, pp. 183-186.
Tripathi S, Ammini AC, Bhatia R, Gupta R, Berry M, Sarkar C et al. Cushing's disease: Pituitary imaging. Australasian Radiology. 1994 Jan 1;38(3):183-186.
Tripathi, S. ; Ammini, A. C. ; Bhatia, Rita ; Gupta, R. ; Berry, M. ; Sarkar, C. ; Mahajan, H. / Cushing's disease : Pituitary imaging. In: Australasian Radiology. 1994 ; Vol. 38, No. 3. pp. 183-186.
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