Current treatment strategies in pediatric gastrointestinal stromal cell tumor

Brent A. Willobee, Hallie J. Quiroz, Matthew S. Sussman, Chad M. Thorson, Juan E Sola, Eduardo Perez

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Gastrointestinal stromal tumors (GIST) are exceedingly rare tumors in the pediatric population. As a result, many clinicians either may never see this diagnosis or will encounter it only a few times throughout their careers. Additionally, the more we discover about this disease, it becomes evident that it represents a distinct clinical entity from adult GIST. Many of the treatments and strategies used to combat the adult tumor are either ineffective or may be harmful to the pediatric population with this disease. The unique tumor biology found in pediatric GIST necessitates unique approaches and treatment strategies in order to achieve the best clinical outcome. This review aims to discuss the most recent data available on the different therapeutic modalities utilized in cases of Pediatric GIST.

Original languageEnglish (US)
Article number53
Pages (from-to)3DUMMY
JournalTranslational Gastroenterology and Hepatology
Volume3
Issue numberAugust
DOIs
StatePublished - Aug 1 2018

Fingerprint

Gastrointestinal Stromal Tumors
Stromal Cells
Pediatrics
Neoplasms
Population
Therapeutics

Keywords

  • Gastrointestinal stromal tumor (GIST)
  • Pediatric
  • Review
  • Treatment
  • Wild-type (WT)

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Current treatment strategies in pediatric gastrointestinal stromal cell tumor. / Willobee, Brent A.; Quiroz, Hallie J.; Sussman, Matthew S.; Thorson, Chad M.; Sola, Juan E; Perez, Eduardo.

In: Translational Gastroenterology and Hepatology, Vol. 3, No. August, 53, 01.08.2018, p. 3DUMMY.

Research output: Contribution to journalReview article

Willobee, Brent A. ; Quiroz, Hallie J. ; Sussman, Matthew S. ; Thorson, Chad M. ; Sola, Juan E ; Perez, Eduardo. / Current treatment strategies in pediatric gastrointestinal stromal cell tumor. In: Translational Gastroenterology and Hepatology. 2018 ; Vol. 3, No. August. pp. 3DUMMY.
@article{851afe3ea6f345a491486753e6d01273,
title = "Current treatment strategies in pediatric gastrointestinal stromal cell tumor",
abstract = "Gastrointestinal stromal tumors (GIST) are exceedingly rare tumors in the pediatric population. As a result, many clinicians either may never see this diagnosis or will encounter it only a few times throughout their careers. Additionally, the more we discover about this disease, it becomes evident that it represents a distinct clinical entity from adult GIST. Many of the treatments and strategies used to combat the adult tumor are either ineffective or may be harmful to the pediatric population with this disease. The unique tumor biology found in pediatric GIST necessitates unique approaches and treatment strategies in order to achieve the best clinical outcome. This review aims to discuss the most recent data available on the different therapeutic modalities utilized in cases of Pediatric GIST.",
keywords = "Gastrointestinal stromal tumor (GIST), Pediatric, Review, Treatment, Wild-type (WT)",
author = "Willobee, {Brent A.} and Quiroz, {Hallie J.} and Sussman, {Matthew S.} and Thorson, {Chad M.} and Sola, {Juan E} and Eduardo Perez",
year = "2018",
month = "8",
day = "1",
doi = "10.21037/tgh.2018.07.09",
language = "English (US)",
volume = "3",
pages = "3DUMMY",
journal = "Translational Gastroenterology and Hepatology",
issn = "2224-476X",
publisher = "AME Publishing Company",
number = "August",

}

TY - JOUR

T1 - Current treatment strategies in pediatric gastrointestinal stromal cell tumor

AU - Willobee, Brent A.

AU - Quiroz, Hallie J.

AU - Sussman, Matthew S.

AU - Thorson, Chad M.

AU - Sola, Juan E

AU - Perez, Eduardo

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Gastrointestinal stromal tumors (GIST) are exceedingly rare tumors in the pediatric population. As a result, many clinicians either may never see this diagnosis or will encounter it only a few times throughout their careers. Additionally, the more we discover about this disease, it becomes evident that it represents a distinct clinical entity from adult GIST. Many of the treatments and strategies used to combat the adult tumor are either ineffective or may be harmful to the pediatric population with this disease. The unique tumor biology found in pediatric GIST necessitates unique approaches and treatment strategies in order to achieve the best clinical outcome. This review aims to discuss the most recent data available on the different therapeutic modalities utilized in cases of Pediatric GIST.

AB - Gastrointestinal stromal tumors (GIST) are exceedingly rare tumors in the pediatric population. As a result, many clinicians either may never see this diagnosis or will encounter it only a few times throughout their careers. Additionally, the more we discover about this disease, it becomes evident that it represents a distinct clinical entity from adult GIST. Many of the treatments and strategies used to combat the adult tumor are either ineffective or may be harmful to the pediatric population with this disease. The unique tumor biology found in pediatric GIST necessitates unique approaches and treatment strategies in order to achieve the best clinical outcome. This review aims to discuss the most recent data available on the different therapeutic modalities utilized in cases of Pediatric GIST.

KW - Gastrointestinal stromal tumor (GIST)

KW - Pediatric

KW - Review

KW - Treatment

KW - Wild-type (WT)

UR - http://www.scopus.com/inward/record.url?scp=85051764540&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85051764540&partnerID=8YFLogxK

U2 - 10.21037/tgh.2018.07.09

DO - 10.21037/tgh.2018.07.09

M3 - Review article

AN - SCOPUS:85051764540

VL - 3

SP - 3DUMMY

JO - Translational Gastroenterology and Hepatology

JF - Translational Gastroenterology and Hepatology

SN - 2224-476X

IS - August

M1 - 53

ER -