Current techniques in diagnostic vitrectomy for uveitis

Steven Yeh, Thomas A Albini, Eric D. Weichel

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Patients with endogenous intermediate uveitis, posterior uveitis, and panuveitis may present diagnostic dilemmas for the retinal and ocular inflammatory specialist. The differential diagnosis for some of these conditions is vast but may include infectious, inflammatory, and neoplastic conditions, some of which may have vision- or life-threatening consequences. Although an array of laboratory and serological tests are available to assist in the diagnosis, some conditions (ie, intraocular lymphoma) require a tissue diagnosis via a vitreous or chorioretinal biopsy. Infectious uveitides may be diagnosed by routine Gram stain and culture techniques of vitreous fluid in some cases; however, antibody- and polymerase chain reaction-based tests are also available and extremely valuable for the diagnosis of infectious entities, which are slow growing or difficult to culture (viruses, mycobacteria, toxoplasmosis). Understanding the currently available tests for vitreous fluid, the parameters for vitreous fluid collection, and the need for communication with an expert ophthalmic pathologist is essential in clinching the diagnosis. Advances in vitrectomy instrumentation and the advent of small-gauge (23- and 25-gauge) vitrectomy techniques will likely aid the treating physician in obtaining vitreous and chorioretinal biopsy specimens in the future.

Original languageEnglish
Pages (from-to)119-127
Number of pages9
JournalTechniques in Ophthalmology
Volume6
Issue number4
DOIs
StatePublished - Dec 1 2008

Fingerprint

Vitrectomy
Uveitis
Intraocular Lymphoma
Intermediate Uveitis
Panuveitis
Posterior Uveitis
Biopsy
Culture Techniques
Toxoplasmosis
Serologic Tests
Mycobacterium
Differential Diagnosis
Communication
Viruses
Physicians
Polymerase Chain Reaction
Antibodies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Current techniques in diagnostic vitrectomy for uveitis. / Yeh, Steven; Albini, Thomas A; Weichel, Eric D.

In: Techniques in Ophthalmology, Vol. 6, No. 4, 01.12.2008, p. 119-127.

Research output: Contribution to journalArticle

Yeh, Steven ; Albini, Thomas A ; Weichel, Eric D. / Current techniques in diagnostic vitrectomy for uveitis. In: Techniques in Ophthalmology. 2008 ; Vol. 6, No. 4. pp. 119-127.
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