TY - JOUR
T1 - Current applications of precision medicine
T2 - A bibliometric analysis
AU - Williams, Jessica R.
AU - Lorenzo, Dalia
AU - Salerno, John
AU - Yeh, Vivian M.
AU - Mitrani, Victoria B.
AU - Kripalani, Sunil
N1 - Funding Information:
Research reported in this publication was conducted under the auspices of the Precision Medicine and Health Disparities Collaborative (Vanderbilt-Meharry-Miami Center of Excellence in Precision Medicine and Population Health), supported by NIMHD and NHGRI of the NIH under award number U54MD010722. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.
PY - 2019
Y1 - 2019
N2 - A bibliometric analysis was conducted to describe trends in the publication of precision medicine literature over time. Searches identified 5552 articles with exponential growth from 2012 to 2018. Most were published in medical specialty journals, particularly oncology. Precision medicine definitions focused on tailored/individualized/personalized treatments and genetics/biology. Little attention was given to social and environmental determinants of health and health disparities. To fulfill the promise of precision medicine to positively impact broad populations, work is needed to develop the science of precision medicine for addressing health disparities and social and environmental determinants of health. While some precision medicine definitions include all factors that contribute to individual differences in health (e.g., genes, environments and lifestyles), future empirical work that includes and integrates all three areas is also required.
AB - A bibliometric analysis was conducted to describe trends in the publication of precision medicine literature over time. Searches identified 5552 articles with exponential growth from 2012 to 2018. Most were published in medical specialty journals, particularly oncology. Precision medicine definitions focused on tailored/individualized/personalized treatments and genetics/biology. Little attention was given to social and environmental determinants of health and health disparities. To fulfill the promise of precision medicine to positively impact broad populations, work is needed to develop the science of precision medicine for addressing health disparities and social and environmental determinants of health. While some precision medicine definitions include all factors that contribute to individual differences in health (e.g., genes, environments and lifestyles), future empirical work that includes and integrates all three areas is also required.
KW - bibliometric analysis
KW - environmental determinants of health
KW - health disparities
KW - health equity
KW - personalized medicine
KW - precision health
KW - precision medicine
KW - social determinants of health
KW - systematic review
UR - http://www.scopus.com/inward/record.url?scp=85070188274&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070188274&partnerID=8YFLogxK
U2 - 10.2217/pme-2018-0089
DO - 10.2217/pme-2018-0089
M3 - Review article
C2 - 31267841
AN - SCOPUS:85070188274
VL - 16
SP - 351
EP - 359
JO - Personalized Medicine
JF - Personalized Medicine
SN - 1741-0541
IS - 4
ER -