Current applications of MRI-guided laser interstitial thermal therapy in the treatment of brain neoplasms and epilepsy

A radiologic and neurosurgical overview

R. Medvid, A. Ruiz, Ricardo J Komotar, Jonathan Jagid, M. E. Ivan, Robert Quencer, Mehul Desai

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

Minimally invasive stereotactic tumor ablation is a viable option for the treatment of benign and malignant intracranial lesions. Although surgical excision constitutes first-line therapy for various brain pathologies, it can cause irreversible neurologic deficits. Additionally, many patients who may benefit from surgery do not qualify as surgical candidates due to multiple comorbidities. Recent advancements in laser interstitial thermal therapy, namely the ability to monitor ablation in real-time underMRimaging, have improved the safety and efficacy of the procedure. MRI-guided laser interstitial thermal therapy is currently used as a minimally invasive treatment for brain metastases, radiation necrosis, glioma, and epilepsy. This article will discuss the principles, suggested indications, complications, and imaging characteristics of MRI-guided laser interstitial thermal therapy as they pertain to the treatment of brain pathology.

Original languageEnglish (US)
Pages (from-to)1998-2006
Number of pages9
JournalAmerican Journal of Neuroradiology
Volume36
Issue number11
DOIs
StatePublished - Nov 1 2015

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Brain Neoplasms
Epilepsy
Lasers
Hot Temperature
Therapeutics
Brain
Pathology
Neurologic Manifestations
Glioma
Comorbidity
Necrosis
Radiation
Neoplasm Metastasis
Safety
Neoplasms

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging

Cite this

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