Current and Emerging Therapies for Itch Management in Psoriasis

Carolyn Stull, Shoshana Grossman, Gil Yosipovitch

Research output: Contribution to journalReview article

13 Scopus citations

Abstract

Pruritus is a common and significant symptom among patients with psoriasis. Pruritus is often present beyond the borders of psoriatic plaques, and frequently affects the scalp and genital regions. Psoriatic itch may be severe and can profoundly affect quality of life and sleep, even in the context of mild-to-moderate disease. These features often make the treatment of psoriatic pruritus challenging. However, there are a variety of effective topical and systemic treatment modalities available to address this symptom. While there remains a need for treatments that specifically target psoriatic itch, newly licensed therapies including secukinumab, ixekizumab and apremilast have been shown to rapidly and effectively mediate itch reduction.

Original languageEnglish (US)
Pages (from-to)617-624
Number of pages8
JournalAmerican Journal of Clinical Dermatology
Volume17
Issue number6
DOIs
StatePublished - Dec 1 2016
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology

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