Culture-positive endophthalmitis after open globe injuries with and without retained intraocular foreign bodies

Tanuj P. Banker, Andrew J. McClellan, Benjamin D. Wilson, Fabiana M. Juan, Ajay E. Kuriyan, Nidhi Relhan, Felix V. Chen, Eric D. Weichel, Thomas A. Albini, Audina M. Berrocal, Jay Sridhar, Ninel Z. Gregori, Justin H. Townsend, Harry W. Flynn

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


BACKGROUND AND OBJECTIVE: To report the visual and anatomical outcomes and microbiologic spectrum of culture-positive endophthalmitis in open globe injuries (OGIs) with or without intraocular foreign bodies (IOFBs). PATIENTS AND METHODS: A retrospective, interventional case series of OGIs (n = 718) treated between 2004 and 2015. Patients underwent a management protocol for OGI, including systemic broad-spectrum antibiotics, on presentation. RESULTS: Culture-positive cases of endophthalmitis after open globe repair occurred in 2.1% of eyes (n = 15 of 718 eyes); two eyes had evidence of endophthalmitis on presentation. The most common organism was Staphylococcus species (five of 17 eyes). An IOFB was present in 6.8% of eyes (n = 49 of 718 eyes). All of these eyes received prophylactic intravitreal antimicrobials. In eyes with IOFB, the rate of culture-positive endophthalmitis after initial globe repair was 8.1% (n = 4 of 49 eyes) versus 1.6% (n = 11 of 669 eyes) in eyes without IOFB (P < .01). CONCLUSION: Culture-positive endophthalmitis was identified after OGIs more often in eyes with a concurrent IOFB.

Original languageEnglish (US)
Pages (from-to)632-637
Number of pages6
JournalOphthalmic Surgery Lasers and Imaging Retina
Issue number8
StatePublished - Aug 2017

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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