TY - JOUR
T1 - CT demonstration of sarcoidosis of the optic nerve, frontal lobes, and Falx cerebri
T2 - Case report and literature review
AU - Post, M. J.D.
AU - Quencer, R. M.
AU - Tabei, S. Z.
PY - 1982/12/1
Y1 - 1982/12/1
N2 - The authors have reported a 39-year-old woman who developed headaches, recurrent seizures, hemiparesis, hemianesthesia, anosmia, and visual loss over a 2 1/2 years period. Diagnosis of sarcoidosis was established by histologic confirmation of a right frontal lobe granuloma and of two skin lesions. Multisystem disease was documented by abnormal chest films, gallium scan, and elevated serum immunoglobulins and prolactin. Serial CT scans over a 27 month period allowed them to see the evolution of neurosarcoidosis and to discover two CT features of this disease. To the CT findings already described in the literature as being highly suggestive of sarcoidosis, they would add the following: abnormal contrast uptake in an enlarged optic nerve and/or chiasm and dense nodular enhancement of a thickened, irregular falx. These additional abnormalities, as illustrated by their case, can be of considerable diagnostic aid since the presence of multiple abnormalities on CT adds specificity to the diagnosis of neurosarcoidosis.
AB - The authors have reported a 39-year-old woman who developed headaches, recurrent seizures, hemiparesis, hemianesthesia, anosmia, and visual loss over a 2 1/2 years period. Diagnosis of sarcoidosis was established by histologic confirmation of a right frontal lobe granuloma and of two skin lesions. Multisystem disease was documented by abnormal chest films, gallium scan, and elevated serum immunoglobulins and prolactin. Serial CT scans over a 27 month period allowed them to see the evolution of neurosarcoidosis and to discover two CT features of this disease. To the CT findings already described in the literature as being highly suggestive of sarcoidosis, they would add the following: abnormal contrast uptake in an enlarged optic nerve and/or chiasm and dense nodular enhancement of a thickened, irregular falx. These additional abnormalities, as illustrated by their case, can be of considerable diagnostic aid since the presence of multiple abnormalities on CT adds specificity to the diagnosis of neurosarcoidosis.
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M3 - Review article
C2 - 6814217
AN - SCOPUS:0020452076
VL - 3
SP - 523
EP - 526
JO - American Journal of Neuroradiology
JF - American Journal of Neuroradiology
SN - 0195-6108
IS - 5
ER -