CT demonstration of sarcoidosis of the optic nerve, frontal lobes, and Falx cerebri

Case report and literature review

M. Judith Post, Robert Quencer, S. Z. Tabei

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The authors have reported a 39-year-old woman who developed headaches, recurrent seizures, hemiparesis, hemianesthesia, anosmia, and visual loss over a 2 1/2 years period. Diagnosis of sarcoidosis was established by histologic confirmation of a right frontal lobe granuloma and of two skin lesions. Multisystem disease was documented by abnormal chest films, gallium scan, and elevated serum immunoglobulins and prolactin. Serial CT scans over a 27 month period allowed them to see the evolution of neurosarcoidosis and to discover two CT features of this disease. To the CT findings already described in the literature as being highly suggestive of sarcoidosis, they would add the following: abnormal contrast uptake in an enlarged optic nerve and/or chiasm and dense nodular enhancement of a thickened, irregular falx. These additional abnormalities, as illustrated by their case, can be of considerable diagnostic aid since the presence of multiple abnormalities on CT adds specificity to the diagnosis of neurosarcoidosis.

Original languageEnglish
Pages (from-to)523-526
Number of pages4
JournalAmerican Journal of Neuroradiology
Volume3
Issue number5
StatePublished - Dec 1 1982

Fingerprint

Frontal Lobe
Sarcoidosis
Optic Nerve
Spinal Cord
Olfaction Disorders
Multiple Abnormalities
Optic Chiasm
Gallium
Paresis
Motion Pictures
Granuloma
Prolactin
Headache
Immunoglobulins
Seizures
Thorax
Skin
Serum
Neurosarcoidosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

CT demonstration of sarcoidosis of the optic nerve, frontal lobes, and Falx cerebri : Case report and literature review. / Judith Post, M.; Quencer, Robert; Tabei, S. Z.

In: American Journal of Neuroradiology, Vol. 3, No. 5, 01.12.1982, p. 523-526.

Research output: Contribution to journalArticle

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