Crosslinked polymers for correction of myopia

Franck Villain, Jean-Marie A Parel, Koichi Yonemura, Gabriel Simon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

When gamma ray crosslinked, PEO gels implanted in the cornea do not cause tissue necrosis resulting in implant expulsion. PEO is not colonized or infiltrated by cells and is mechanically and optically stable. One of the most important advantage using gels is that at any postoperative times, the track's volume can easily be augmented or decreased to finely adjust the refractive correction and, if need be, totally removed from the track. With PEO, GIAK is a safe procedure. A corneal implant designed to correct myopia should have and give a long trouble-free life, as surgery might occur as early as age 20. Therefore even if performed in a short lived animal (cat) a 28 months study cannot be considered a `long' term follow-up. As the cat cornea differs both mechanically and morphologically from man, a human DFA phase I pilot study is necessary.

Original languageEnglish (US)
Title of host publicationPolymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering
Editors Anon
PublisherPubl by ACS
Pages537-538
Number of pages2
Volume69
StatePublished - 1993
EventProceedings of the American Chemical Society Division of Polymeric Materials - Science and Engineering - Chicago, IL, USA
Duration: Jun 11 1993Jun 11 1993

Other

OtherProceedings of the American Chemical Society Division of Polymeric Materials - Science and Engineering
CityChicago, IL, USA
Period6/11/936/11/93

Fingerprint

Polyethylene oxides
Polymers
Gels
Gamma rays
Surgery
Animals
Tissue

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Polymers and Plastics

Cite this

Villain, F., Parel, J-M. A., Yonemura, K., & Simon, G. (1993). Crosslinked polymers for correction of myopia. In Anon (Ed.), Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering (Vol. 69, pp. 537-538). Publ by ACS.

Crosslinked polymers for correction of myopia. / Villain, Franck; Parel, Jean-Marie A; Yonemura, Koichi; Simon, Gabriel.

Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering. ed. / Anon. Vol. 69 Publ by ACS, 1993. p. 537-538.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Villain, F, Parel, J-MA, Yonemura, K & Simon, G 1993, Crosslinked polymers for correction of myopia. in Anon (ed.), Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering. vol. 69, Publ by ACS, pp. 537-538, Proceedings of the American Chemical Society Division of Polymeric Materials - Science and Engineering, Chicago, IL, USA, 6/11/93.
Villain F, Parel J-MA, Yonemura K, Simon G. Crosslinked polymers for correction of myopia. In Anon, editor, Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering. Vol. 69. Publ by ACS. 1993. p. 537-538
Villain, Franck ; Parel, Jean-Marie A ; Yonemura, Koichi ; Simon, Gabriel. / Crosslinked polymers for correction of myopia. Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering. editor / Anon. Vol. 69 Publ by ACS, 1993. pp. 537-538
@inproceedings{e7eed1d31c0e4605b4fe001057fee8f7,
title = "Crosslinked polymers for correction of myopia",
abstract = "When gamma ray crosslinked, PEO gels implanted in the cornea do not cause tissue necrosis resulting in implant expulsion. PEO is not colonized or infiltrated by cells and is mechanically and optically stable. One of the most important advantage using gels is that at any postoperative times, the track's volume can easily be augmented or decreased to finely adjust the refractive correction and, if need be, totally removed from the track. With PEO, GIAK is a safe procedure. A corneal implant designed to correct myopia should have and give a long trouble-free life, as surgery might occur as early as age 20. Therefore even if performed in a short lived animal (cat) a 28 months study cannot be considered a `long' term follow-up. As the cat cornea differs both mechanically and morphologically from man, a human DFA phase I pilot study is necessary.",
author = "Franck Villain and Parel, {Jean-Marie A} and Koichi Yonemura and Gabriel Simon",
year = "1993",
language = "English (US)",
volume = "69",
pages = "537--538",
editor = "Anon",
booktitle = "Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering",
publisher = "Publ by ACS",

}

TY - GEN

T1 - Crosslinked polymers for correction of myopia

AU - Villain, Franck

AU - Parel, Jean-Marie A

AU - Yonemura, Koichi

AU - Simon, Gabriel

PY - 1993

Y1 - 1993

N2 - When gamma ray crosslinked, PEO gels implanted in the cornea do not cause tissue necrosis resulting in implant expulsion. PEO is not colonized or infiltrated by cells and is mechanically and optically stable. One of the most important advantage using gels is that at any postoperative times, the track's volume can easily be augmented or decreased to finely adjust the refractive correction and, if need be, totally removed from the track. With PEO, GIAK is a safe procedure. A corneal implant designed to correct myopia should have and give a long trouble-free life, as surgery might occur as early as age 20. Therefore even if performed in a short lived animal (cat) a 28 months study cannot be considered a `long' term follow-up. As the cat cornea differs both mechanically and morphologically from man, a human DFA phase I pilot study is necessary.

AB - When gamma ray crosslinked, PEO gels implanted in the cornea do not cause tissue necrosis resulting in implant expulsion. PEO is not colonized or infiltrated by cells and is mechanically and optically stable. One of the most important advantage using gels is that at any postoperative times, the track's volume can easily be augmented or decreased to finely adjust the refractive correction and, if need be, totally removed from the track. With PEO, GIAK is a safe procedure. A corneal implant designed to correct myopia should have and give a long trouble-free life, as surgery might occur as early as age 20. Therefore even if performed in a short lived animal (cat) a 28 months study cannot be considered a `long' term follow-up. As the cat cornea differs both mechanically and morphologically from man, a human DFA phase I pilot study is necessary.

UR - http://www.scopus.com/inward/record.url?scp=0027850444&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027850444&partnerID=8YFLogxK

M3 - Conference contribution

VL - 69

SP - 537

EP - 538

BT - Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering

A2 - Anon, null

PB - Publ by ACS

ER -