Crohn's disease complicated by primary gastrointestinal Hodgkin's lymphoma presenting with small bowel perforation

Aurelio Castrellon, Paul Andrew Feldman, Miguel Suarez, Seth Spector, Lucy Chua, John Byrnes

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

An increased incidence of non-Hodgkin's lymphoma has been reported in patients with inflammatory bowel disease, particularly in those receiving immunosuppressive therapy. Rare cases of Hodgkin's lymphoma have been reported in a setting of inflammatory bowel disease. The mechanism underlying the apparent association is unclear, but alterations in immune surveillance could play a role. In this report we describe the clinicopathological features of primary gastrointestinal Hodgkin's lymphoma diagnosed in a patient with Crohn's ileocolitis who had been receiving therapy with immunomodulator and biologic therapies.

Original languageEnglish (US)
Pages (from-to)359-361
Number of pages3
JournalJournal of Gastrointestinal and Liver Diseases
Volume18
Issue number3
StatePublished - Dec 1 2009

Keywords

  • Anti-TNF therapy
  • Crohn's disease
  • Hodgkin's lymphoma
  • Immunomodulators

ASJC Scopus subject areas

  • Gastroenterology

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