Crofelemer for the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy

Jose G Castro, Nafeesa Chin-Beckford

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Chronic diarrhea remains a common condition that affects people infected with human immunodeficiency virus (HIV) despite the widespread use of potent antiretroviral therapy. It is important that providers control this condition, as the persistence of diarrhea affects the quality of life of patients and may contribute to decreased adherence to antiretroviral therapy. Strategies to control diarrhea in patients with HIV infection include switching to a new antiretroviral regimen and/or the use of specific medications to control the diarrhea. This review aims to provide a concise evaluation of a newly approved medication (crofelemer) that has a novel mechanism of action and has received approval for the symptomatic relief of non-infectious diarrhea in adult patients with HIV on anti-retroviral therapy.

Original languageEnglish (US)
Pages (from-to)683-690
Number of pages8
JournalExpert Review of Clinical Pharmacology
Volume8
Issue number6
DOIs
StatePublished - Nov 2 2015

Keywords

  • AIDS
  • crofelemer
  • diarrhea
  • HIV
  • secretory diarrhea
  • side effects antiretrovirals
  • treatment diarrhea

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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