Creutzfeldt-Jakob disease in a recipient of a dura mater graft processed in the US: Cause or coincidence?

James G. Dobbins; Ermias D. Belay; Jean Malecki; Bill E. Buck; Michael Bell; Judy Cobb; Lawrence B. Schonberger

doi:10.1159/000026240

Creutzfeldt-Jakob disease in a recipient of a dura mater graft processed in the US: Cause or coincidence?

James G. Dobbins, Ermias D. Belay, Jean Malecki, Bill E. Buck, Michael Bell, Judy Cobb, Lawrence B. Schonberger

Department Of Orthopaedics

Research output: Contribution to journal › Article

7 Scopus citations

Abstract

Iatrogenic Creutzfeldt-Jakob disease (CJD) has never been reported among recipients of dura mater grafts processed in the US. We recently investigated a report of such a case in a 72-year-old man with a typical clinical presentation of CJD. We found no evidence of CJD in either the 34-year-old donor or in other, proximal patients undergoing craniotomies. Although the graft may have caused the illness, sporadic CJD is a more likely explanation, with the graft being coincidental. Copyright (C) 2000 S. Karger AG, Basel.

Original language	English (US)
Pages (from-to)	62-66
Number of pages	5
Journal	Neuroepidemiology
Volume	19
Issue number	2
DOIs	https://doi.org/10.1159/000026240
State	Published - Jan 1 2000

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Keywords

Creutzfeldt-Jakob disease
Dura mater
Epidemiology

ASJC Scopus subject areas

Epidemiology
Clinical Neurology

Cite this

Dobbins, J. G., Belay, E. D., Malecki, J., Buck, B. E., Bell, M., Cobb, J., & Schonberger, L. B. (2000). Creutzfeldt-Jakob disease in a recipient of a dura mater graft processed in the US: Cause or coincidence? Neuroepidemiology, 19(2), 62-66. https://doi.org/10.1159/000026240

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abstract = "Iatrogenic Creutzfeldt-Jakob disease (CJD) has never been reported among recipients of dura mater grafts processed in the US. We recently investigated a report of such a case in a 72-year-old man with a typical clinical presentation of CJD. We found no evidence of CJD in either the 34-year-old donor or in other, proximal patients undergoing craniotomies. Although the graft may have caused the illness, sporadic CJD is a more likely explanation, with the graft being coincidental. Copyright (C) 2000 S. Karger AG, Basel.",

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10.1159/000026240