Creutzfeldt-Jakob Disease from allogeneic dura: A review of risks and safety

Robert E. Marx, Eric R. Carlson

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Surgeons and the lay public have recently expressed concern over the safety of allogeneic dura as it relates to the transmission of Creutzfeldt-Jakob Disease. Indeed, two cases have resulted from use of tissue procured from a commercial agency that did not adhere to criteria accepted by the American Association of Tissue Banks or the Southeast Organ Procurement Foundation. This review discusses the risks and safety of allogeneic dura. The findings should reassure the surgeon of the safety of allogeneic dura when it is properly processed and catalogued by abona fide, reputable tissue bank. To date, there have been no documented cases reported to the Center for Disease Control in which Creutzfeldt-Jakob Disease was transmitted from allogeneic dura obtained from a registered tissue bank.

Original languageEnglish (US)
Pages (from-to)272-274
Number of pages3
JournalJournal of Oral and Maxillofacial Surgery
Issue number3
StatePublished - Mar 1991

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology


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