Cranial bone grafting: Biodegradable versus titanium fixation in a rabbit model

Seth R. Thaller, Carmen Moore, Henry Tesluk, Ralph Holmes

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Rigid internal fixation with miniplates and screws has enabled reconstructive surgeons to position bony segments precisely. Unfortunately, our present systems have been associated with a potential adverse effect on ultimate craniofacial growth and development. Also, they may be palpable, necessitating secondary procedures for removal of the hardware. We have been involved in an ongoing study evaluating the efficacy of a commercially developed biodegradable system. In this study, we compared biodegradable lag screw fixation with traditional titanium screw fixation in full-thickness, membranous bone grafts harvested from the zygomatic arches to the snout in a rabbit model. The results were compared with standard hematoxylin and eosin stains and laser densometry. Although this study adds further credence to the resorption of bone grafts, those secured with the polyglycolic acid screws demonstrated significantly less resorption than those maintained in position by traditional methods.

Original languageEnglish (US)
Pages (from-to)54-59
Number of pages6
JournalJournal of Craniofacial Surgery
Issue number1
StatePublished - Jan 1 1996


  • Biodegradable fixation
  • Cranial bone grafts
  • Onlay bone grafting

ASJC Scopus subject areas

  • Surgery


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