Crack cocaine smoking and oral sores in three inner-city neighborhoods

Sairus Faruque, Brian R. Edlin, Clyde B McCoy, Carl O. Word, Sandra A. Larsen, D. Scott Schmid, Jennifer C. Von Bargen, Yolanda Serrano

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Crack cocaine causes blisters, sores, and cuts on the lips and in the mouths of persons who smoke it, and such sores may facilitate the oral transmission of HIV. We recruited young adults aged 18-29 years, who either were current regular crack smokers, or who had never smoked crack, from inner-city neighborhoods in New York, Miami, and San Francisco. Participants were interviewed for HIV risk behaviors and history of recent oral sores and were tested for HIV, syphilis, and herpes simplex virus (HSV) antibodies. Among the 2,323 participants recruited, 1,404 (60%) were crack smokers. Crack smokers (10.0%) were more likely than nonsmokers (4.5%) to report having had oral sores in the past 30 days [prevalence odds ratio (POR) 2.4, 95% confidence interval (CI) 1.7-3.4]. Sores were also more prevalent among those who had ever injected drugs (14.3%) than among those who had not (6.7%; POR 2.3, 95% CI 1.7-3.4), and among those with HIV infection (14.3%) than among those without it (8.0%; POR 1.9, 95% CI 1.3-2.8). Among the 429 participants who reported receptive oral sex, those who reported oral sores were more likely than those who did not to have HIV infection, after other HIV risk factors were controlled for (adjusted POR 1.9, 95% CI 1.0-3.6). Our results confirm that crack smokers have a high prevalence of oral sores and provides evidence that these sores, although infrequently, may facilitate oral transmission of HIV.

Original languageEnglish
Pages (from-to)87-92
Number of pages6
JournalJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Volume13
Issue number1
StatePublished - Oct 7 1996

Fingerprint

Crack Cocaine
Smoking
HIV
Odds Ratio
Confidence Intervals
HIV Infections
San Francisco
Simplexvirus
Blister
Syphilis
Lip
Risk-Taking
Smoke
Sexual Behavior
Mouth
Young Adult
Interviews
Antibodies
Pharmaceutical Preparations

Keywords

  • Crack cocaine
  • HIV infection
  • HIV transmission
  • Oral sex
  • Oral sores

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Virology

Cite this

Faruque, S., Edlin, B. R., McCoy, C. B., Word, C. O., Larsen, S. A., Schmid, D. S., ... Serrano, Y. (1996). Crack cocaine smoking and oral sores in three inner-city neighborhoods. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 13(1), 87-92.

Crack cocaine smoking and oral sores in three inner-city neighborhoods. / Faruque, Sairus; Edlin, Brian R.; McCoy, Clyde B; Word, Carl O.; Larsen, Sandra A.; Schmid, D. Scott; Von Bargen, Jennifer C.; Serrano, Yolanda.

In: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, Vol. 13, No. 1, 07.10.1996, p. 87-92.

Research output: Contribution to journalArticle

Faruque, S, Edlin, BR, McCoy, CB, Word, CO, Larsen, SA, Schmid, DS, Von Bargen, JC & Serrano, Y 1996, 'Crack cocaine smoking and oral sores in three inner-city neighborhoods', Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, vol. 13, no. 1, pp. 87-92.
Faruque, Sairus ; Edlin, Brian R. ; McCoy, Clyde B ; Word, Carl O. ; Larsen, Sandra A. ; Schmid, D. Scott ; Von Bargen, Jennifer C. ; Serrano, Yolanda. / Crack cocaine smoking and oral sores in three inner-city neighborhoods. In: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 1996 ; Vol. 13, No. 1. pp. 87-92.
@article{a62d2abcaaab4e72bb73a95999a8268e,
title = "Crack cocaine smoking and oral sores in three inner-city neighborhoods",
abstract = "Crack cocaine causes blisters, sores, and cuts on the lips and in the mouths of persons who smoke it, and such sores may facilitate the oral transmission of HIV. We recruited young adults aged 18-29 years, who either were current regular crack smokers, or who had never smoked crack, from inner-city neighborhoods in New York, Miami, and San Francisco. Participants were interviewed for HIV risk behaviors and history of recent oral sores and were tested for HIV, syphilis, and herpes simplex virus (HSV) antibodies. Among the 2,323 participants recruited, 1,404 (60{\%}) were crack smokers. Crack smokers (10.0{\%}) were more likely than nonsmokers (4.5{\%}) to report having had oral sores in the past 30 days [prevalence odds ratio (POR) 2.4, 95{\%} confidence interval (CI) 1.7-3.4]. Sores were also more prevalent among those who had ever injected drugs (14.3{\%}) than among those who had not (6.7{\%}; POR 2.3, 95{\%} CI 1.7-3.4), and among those with HIV infection (14.3{\%}) than among those without it (8.0{\%}; POR 1.9, 95{\%} CI 1.3-2.8). Among the 429 participants who reported receptive oral sex, those who reported oral sores were more likely than those who did not to have HIV infection, after other HIV risk factors were controlled for (adjusted POR 1.9, 95{\%} CI 1.0-3.6). Our results confirm that crack smokers have a high prevalence of oral sores and provides evidence that these sores, although infrequently, may facilitate oral transmission of HIV.",
keywords = "Crack cocaine, HIV infection, HIV transmission, Oral sex, Oral sores",
author = "Sairus Faruque and Edlin, {Brian R.} and McCoy, {Clyde B} and Word, {Carl O.} and Larsen, {Sandra A.} and Schmid, {D. Scott} and {Von Bargen}, {Jennifer C.} and Yolanda Serrano",
year = "1996",
month = "10",
day = "7",
language = "English",
volume = "13",
pages = "87--92",
journal = "Journal of acquired immune deficiency syndromes (1999)",
issn = "1525-4135",
publisher = "Lippincott Williams and Wilkins Ltd.",
number = "1",

}

TY - JOUR

T1 - Crack cocaine smoking and oral sores in three inner-city neighborhoods

AU - Faruque, Sairus

AU - Edlin, Brian R.

AU - McCoy, Clyde B

AU - Word, Carl O.

AU - Larsen, Sandra A.

AU - Schmid, D. Scott

AU - Von Bargen, Jennifer C.

AU - Serrano, Yolanda

PY - 1996/10/7

Y1 - 1996/10/7

N2 - Crack cocaine causes blisters, sores, and cuts on the lips and in the mouths of persons who smoke it, and such sores may facilitate the oral transmission of HIV. We recruited young adults aged 18-29 years, who either were current regular crack smokers, or who had never smoked crack, from inner-city neighborhoods in New York, Miami, and San Francisco. Participants were interviewed for HIV risk behaviors and history of recent oral sores and were tested for HIV, syphilis, and herpes simplex virus (HSV) antibodies. Among the 2,323 participants recruited, 1,404 (60%) were crack smokers. Crack smokers (10.0%) were more likely than nonsmokers (4.5%) to report having had oral sores in the past 30 days [prevalence odds ratio (POR) 2.4, 95% confidence interval (CI) 1.7-3.4]. Sores were also more prevalent among those who had ever injected drugs (14.3%) than among those who had not (6.7%; POR 2.3, 95% CI 1.7-3.4), and among those with HIV infection (14.3%) than among those without it (8.0%; POR 1.9, 95% CI 1.3-2.8). Among the 429 participants who reported receptive oral sex, those who reported oral sores were more likely than those who did not to have HIV infection, after other HIV risk factors were controlled for (adjusted POR 1.9, 95% CI 1.0-3.6). Our results confirm that crack smokers have a high prevalence of oral sores and provides evidence that these sores, although infrequently, may facilitate oral transmission of HIV.

AB - Crack cocaine causes blisters, sores, and cuts on the lips and in the mouths of persons who smoke it, and such sores may facilitate the oral transmission of HIV. We recruited young adults aged 18-29 years, who either were current regular crack smokers, or who had never smoked crack, from inner-city neighborhoods in New York, Miami, and San Francisco. Participants were interviewed for HIV risk behaviors and history of recent oral sores and were tested for HIV, syphilis, and herpes simplex virus (HSV) antibodies. Among the 2,323 participants recruited, 1,404 (60%) were crack smokers. Crack smokers (10.0%) were more likely than nonsmokers (4.5%) to report having had oral sores in the past 30 days [prevalence odds ratio (POR) 2.4, 95% confidence interval (CI) 1.7-3.4]. Sores were also more prevalent among those who had ever injected drugs (14.3%) than among those who had not (6.7%; POR 2.3, 95% CI 1.7-3.4), and among those with HIV infection (14.3%) than among those without it (8.0%; POR 1.9, 95% CI 1.3-2.8). Among the 429 participants who reported receptive oral sex, those who reported oral sores were more likely than those who did not to have HIV infection, after other HIV risk factors were controlled for (adjusted POR 1.9, 95% CI 1.0-3.6). Our results confirm that crack smokers have a high prevalence of oral sores and provides evidence that these sores, although infrequently, may facilitate oral transmission of HIV.

KW - Crack cocaine

KW - HIV infection

KW - HIV transmission

KW - Oral sex

KW - Oral sores

UR - http://www.scopus.com/inward/record.url?scp=0029767469&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029767469&partnerID=8YFLogxK

M3 - Article

C2 - 8797690

AN - SCOPUS:0029767469

VL - 13

SP - 87

EP - 92

JO - Journal of acquired immune deficiency syndromes (1999)

JF - Journal of acquired immune deficiency syndromes (1999)

SN - 1525-4135

IS - 1

ER -