Correlation between the dexamethasone suppression test in depressed patients and clinical response

C. B. Nemeroff, D. L. Evans

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

Eighteen psychiatric inpatients who fulfilled DSM-III criteria for major depression and who had a positive dexamethasone suppression test after admission were later retested. Of the 13 patients who exhibited cortisol suppression at discharge, two relapsed within 6 months; five remained nonsuppressors at discharge, and all either required further inpatient care or were symptomatic within 2 weeks to 4 months. Continued cortisol nonsuppression was thus associated with poor clinical response or high risk of relapse.

Original languageEnglish (US)
Pages (from-to)247-249
Number of pages3
JournalAmerican Journal of Psychiatry
Volume141
Issue number2
DOIs
StatePublished - 1984

ASJC Scopus subject areas

  • Psychiatry and Mental health

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