Correlation between the dexamethasone suppression test in depressed patients and clinical response

Charles Nemeroff, D. L. Evans

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Eighteen psychiatric inpatients who fulfilled DSM-III criteria for major depression and who had a positive dexamethasone suppression test after admission were later retested. Of the 13 patients who exhibited cortisol suppression at discharge, two relapsed within 6 months; five remained nonsuppressors at discharge, and all either required further inpatient care or were symptomatic within 2 weeks to 4 months. Continued cortisol nonsuppression was thus associated with poor clinical response or high risk of relapse.

Original languageEnglish
Pages (from-to)247-249
Number of pages3
JournalAmerican Journal of Psychiatry
Volume141
Issue number2
StatePublished - Jan 1 1984
Externally publishedYes

Fingerprint

Dexamethasone
Hydrocortisone
Inpatients
Diagnostic and Statistical Manual of Mental Disorders
Psychiatry
Recurrence

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Correlation between the dexamethasone suppression test in depressed patients and clinical response. / Nemeroff, Charles; Evans, D. L.

In: American Journal of Psychiatry, Vol. 141, No. 2, 01.01.1984, p. 247-249.

Research output: Contribution to journalArticle

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