Correlation between estrogen receptors and response to nonhormonal chemotherapy in metastatic breast cancer

T. Umsawasdi; Charles Vogel; W. Voigt

Correlation between estrogen receptors and response to nonhormonal chemotherapy in metastatic breast cancer

T. Umsawasdi, Charles Vogel, W. Voigt

Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

While our data do not show a significant difference in response to cytotoxic chemotherapy between ER-positive and ER-negative patients, they clearly do not confirm the results of Lippman and co-workers, and there is a trend for our data to support those of Kiang and associates. We believe that it is unlikely that estrogen receptor assays will prove to have important predictive value for response to cytotoxic chemotherapy. However, more prospective studies published in detail with a larger number of patients will be needed to resolve this issue.

Original language	English
Title of host publication	Breast. Diseases of the Breast
Pages	26-31
Number of pages	6
Volume	7
Edition	2
State	Published - Dec 1 1981

ASJC Scopus subject areas

Medicine(all)

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abstract = "While our data do not show a significant difference in response to cytotoxic chemotherapy between ER-positive and ER-negative patients, they clearly do not confirm the results of Lippman and co-workers, and there is a trend for our data to support those of Kiang and associates. We believe that it is unlikely that estrogen receptor assays will prove to have important predictive value for response to cytotoxic chemotherapy. However, more prospective studies published in detail with a larger number of patients will be needed to resolve this issue.",

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N2 - While our data do not show a significant difference in response to cytotoxic chemotherapy between ER-positive and ER-negative patients, they clearly do not confirm the results of Lippman and co-workers, and there is a trend for our data to support those of Kiang and associates. We believe that it is unlikely that estrogen receptor assays will prove to have important predictive value for response to cytotoxic chemotherapy. However, more prospective studies published in detail with a larger number of patients will be needed to resolve this issue.

AB - While our data do not show a significant difference in response to cytotoxic chemotherapy between ER-positive and ER-negative patients, they clearly do not confirm the results of Lippman and co-workers, and there is a trend for our data to support those of Kiang and associates. We believe that it is unlikely that estrogen receptor assays will prove to have important predictive value for response to cytotoxic chemotherapy. However, more prospective studies published in detail with a larger number of patients will be needed to resolve this issue.

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