TY - JOUR
T1 - Corneal biomechanical properties and intraocular pressure in high myopic anisometropia
AU - Xu, Suzhong
AU - Xu, Aiqin
AU - Tao, Aizhu
AU - Wang, Jianhua
AU - Fan, Fan
AU - Lu, Fan
PY - 2010/7/1
Y1 - 2010/7/1
N2 - ObjectiveS:: To investigate corneal biomechanical properties and intraocular pressure (IOP) in patients with high myopic anisometropia. Methods:: Patients with high myopic anisometropia (n = 23) and emmetropic subjects (n = 55) were enrolled. Corneal hysteresis (CH), Goldmann-correlated intraocular pressure (IOPg), corneal resistance factor, and corneal-compensated IOP (IOPcc) were measured with Ocular Response Analyzer. Central corneal thickness was measured by optical coherence tomography. Zeiss IOL-Master determined the values of corneal refractive power and ocular axial length. Results:: Significant differences were presented in CH, IOPg, and IOPcc among the high myopic, contralateral, and normal eyes (analysis of variance, P<0.05). CH in high myopic eye was lower than that in the other two groups (post hoc, P<0.05), whereas IOPg and IOPcc in both eyes of anisometropic myopia were higher compared with the normal subjects (post hoc, P<0.01). CH was associated with central corneal thickness and axial length in high myopic eyes. All measured biometric parameters showed significant correlations between two eyes in high myopic anisometropia. Conclusions:: High myopic eyes showed decreased CH, but not corneal resistance factor, which indicates that some aspects of corneal biomechanical properties may be altered in high myopic eye of anisometropia. It is also suggested that anisometropic eyes with different refractive errors do not share the same biomechanical properties, which may impact IOP measurement.
AB - ObjectiveS:: To investigate corneal biomechanical properties and intraocular pressure (IOP) in patients with high myopic anisometropia. Methods:: Patients with high myopic anisometropia (n = 23) and emmetropic subjects (n = 55) were enrolled. Corneal hysteresis (CH), Goldmann-correlated intraocular pressure (IOPg), corneal resistance factor, and corneal-compensated IOP (IOPcc) were measured with Ocular Response Analyzer. Central corneal thickness was measured by optical coherence tomography. Zeiss IOL-Master determined the values of corneal refractive power and ocular axial length. Results:: Significant differences were presented in CH, IOPg, and IOPcc among the high myopic, contralateral, and normal eyes (analysis of variance, P<0.05). CH in high myopic eye was lower than that in the other two groups (post hoc, P<0.05), whereas IOPg and IOPcc in both eyes of anisometropic myopia were higher compared with the normal subjects (post hoc, P<0.01). CH was associated with central corneal thickness and axial length in high myopic eyes. All measured biometric parameters showed significant correlations between two eyes in high myopic anisometropia. Conclusions:: High myopic eyes showed decreased CH, but not corneal resistance factor, which indicates that some aspects of corneal biomechanical properties may be altered in high myopic eye of anisometropia. It is also suggested that anisometropic eyes with different refractive errors do not share the same biomechanical properties, which may impact IOP measurement.
KW - Corneal hysteresis
KW - High myopic anisometropia
KW - Intraocular pressure
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U2 - 10.1097/ICL.0b013e3181e4a60a
DO - 10.1097/ICL.0b013e3181e4a60a
M3 - Article
C2 - 20531203
AN - SCOPUS:77954657185
VL - 36
SP - 204
EP - 209
JO - Eye and Contact Lense
JF - Eye and Contact Lense
SN - 1542-2321
IS - 4
ER -