Cord blood serum in newborns of diabetic mothers

Marianna K. Fordyce, Robert Duncan, Robert Chao, Michael Christakis, Sung L. Hsia, Euan Robertson, Anthony Kafatos, George Christakis

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Serum cholesterol, triglycerides and lipoprotein cholesterol were measured in cord bloods from 117 newborns. Group I consisted of 39 infants of diabetic mothers and Group II (control) consisted of 78 newborns of non-diabetic mothers. The most significant difference in serum lipids between the two groups was the higher levels of LDL cholesterol and lower levels of HDL cholesterol in the newborns of diabetic mothers. Cord blood serum cholesterol was slightly, but not significantly, higher in children born of diabetic mothers. Serum triglycerides were also not significantly different between the groups. While it remains to be established whether elevated levels of LDL cholesterol and decreased levels of HDL cholesterol at birth in these infants represent a transient phenomenon, this study suggests that newborns of diabetic mothers may be predisposed early in life to LDL hypercholesterolemia and thus may be at a greater risk of developing coronary heart disease later in life.

Original languageEnglish (US)
Pages (from-to)263-268
Number of pages6
JournalJournal of Chronic Diseases
Volume36
Issue number3
DOIs
StatePublished - 1983

ASJC Scopus subject areas

  • Epidemiology

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    Fordyce, M. K., Duncan, R., Chao, R., Christakis, M., Hsia, S. L., Robertson, E., Kafatos, A., & Christakis, G. (1983). Cord blood serum in newborns of diabetic mothers. Journal of Chronic Diseases, 36(3), 263-268. https://doi.org/10.1016/0021-9681(83)90061-9