Controversies in the surgical treatment of ruptured intracranial aneurysms: The first annual J. Lawrence pool memorial research symposium - Controversies in the management of cerebral aneurysms

Ricardo J Komotar, Brad E. Zacharia, J. Mocco, E. Sander Connolly

Research output: Contribution to journalArticle

17 Scopus citations


THE MANAGEMENT OF aneurysmal subarachnoid hemorrhage has evolved over time, including the use of the microscope for aneurysm clip application, improved imaging modalities, endovascular methods for aneurysm treatment, dedicated neurointensive care units, and more aggressive therapy for cerebral vasospasm. Although these advancements have reduced the morbidity and mortality associated with aneurysmal subarachnoid hemorrhage, outcomes for this patient population continue to leave much room for improvement. This work highlights controversial adjuvant techniques, maneuvers, and therapies surrounding the surgical treatment of ruptured cerebral aneurysms that currently lack a consensus opinion. These treatments include centralized care in high-volume centers, as well as the use of antifibrinolytic therapy, routine cerebrospinal fluid diversion, intraoperative hypothermia, temporary clip application, neuroprotective drugs, intraoperative angiography, and decompressive hemicraniectomy. Although definitive answers will only be possible through future multicenter collaboration, we review the controversy surrounding these adjuncts and report the consensus opinion from a highly experienced audience.

Original languageEnglish
Pages (from-to)396-405
Number of pages10
Issue number2
StatePublished - Feb 1 2008
Externally publishedYes



  • Aneurysmal subarachnoid hemorrhage
  • Antifibrinolytic therapy
  • Centralized care
  • Cerebral aneurysm
  • Hemicraniectomy
  • Hypothermia
  • Neuroprotection
  • Temporary clip

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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