Controversies in experimental dermatology. What controls hair follicle cycling? Viewpoints

Kurt S. Stenn, Alex J. Nixon, Colin A.B. Jahoda, Ian A. McKay, Ralf Paus

Research output: Contribution to journalComment/debate

4 Scopus citations

Abstract

Despite more than a hundred years of professional hair research, and substantial recent progress in unravelling the molecular controls of hair follicle morphogenesis, the chronobiological control system that cyclically drives the hair follicle through dramatic remodelling processes between phases of growth (anagen), regression (catagen), and relative resting (telogen) have remained disappointingly obscure. In view of the vast literature that has become available over the past decades on numerous genetic, biochemical, cellular and pharmacological aspects of hair growth control under physiological and pathological conditions, it is astounding how comparatively few researchers in the field have published theoretical concepts that explore how hair follicle cycling might be controlled. Since this question is at the very heart of basic and clinically applied hair biology, it deserves a much more systematic and serious public exploration, which the following contributions are designed to stimulate.

Original languageEnglish (US)
Pages (from-to)229-233
Number of pages5
JournalExperimental dermatology
Volume8
Issue number4
StatePublished - Jan 1 1999
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology

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  • Cite this

    Stenn, K. S., Nixon, A. J., Jahoda, C. A. B., McKay, I. A., & Paus, R. (1999). Controversies in experimental dermatology. What controls hair follicle cycling? Viewpoints. Experimental dermatology, 8(4), 229-233.