Craniopharyngiomas have historically presented significant surgical challenges, as they are located in the center of the brain and skull base, close to critical structures. Multiple approaches have developed over the years to treat these histologically benign but malignantly behaving tumors, including transcranial and transsphenoidal approaches. Recent advances in endoscopy have allowed surgeons to approach these tumors with extended transsphenoidal approaches which offer unprecedented views and minimal invasiveness. Improvements in closure techniques have helped minimize or eliminate CSF leaks, the main complication of this approach, and patients benefit from avoiding the retraction and seizure risk of an open transcranial procedure. Radiation can also be combined with resection and the optimal strategy of gross total resection or subtotal resection with radiation depends in part on the age of the patient and extent of hypothalamic involvement.
|Original language||English (US)|
|Title of host publication||Craniopharyngiomas|
|Subtitle of host publication||Comprehensive Diagnosis, Treatment and Outcome|
|Number of pages||13|
|State||Published - Jan 8 2015|
ASJC Scopus subject areas