Control of oxygenation during mechanical ventilation in the premature infant

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


Maintenance of oxygen saturation targets is a demanding and tedious task because of the frequency with which oxygenation changes, especially in small infants receiving prolonged respiratory support. It is clear that the achievement of oxygenation targets can be improved by a higher nurse-to-patient ratio and by intense staff training. Automated control systems can also improve target maintenance, and this is achieved mainly by reducing exposure to hyperoxemia. The long-term benefits and safety of this strategy are yet to be determined in clinical trials.

Original languageEnglish (US)
Pages (from-to)563-572
Number of pages10
JournalClinics in Perinatology
Issue number3
StatePublished - Sep 2012


  • Hyperoxemia
  • Hypoxemia
  • Oxygen saturation targets
  • Premature infants
  • Supplemental oxygen

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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