Control of inflammatory processes by cell-impermeable inhibitors of phospholipase A2

S. Yedgar, P. Dan, A. Dagan, I. Ginsburg, I. S. Lossos, R. Breuer

Research output: Contribution to journalArticle

16 Scopus citations


Cell-impermeable inhibitors of phospholipase A2 were prepared by linking inhibiting molecules to macromolecular carriers which prevent the inhibitor's internalization. These preparations inhibit the release of oxygen reactive species from neutrophils and cell death induced by inflammatory agents, as well as bleomycin-induced lung injury.

Original languageEnglish (US)
Pages (from-to)77-84
Number of pages8
JournalAgents and Actions
Issue numberSUPPL.
StatePublished - Jan 1 1995


ASJC Scopus subject areas

  • Toxicology
  • Pharmacology (medical)

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