Control of gonadotropic hormone release in trout: Influence of synthetic LHRH and LHRH analogues in vivo and in vitro

L. W. Crim, D. M. Evans, D. H. Coy, A. V. Schally

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Studies were conducted to determine the influence of some LHRH analogues on gonadotropic hormone (GtH) secretion in two species of trout. The observations indicated that synthetic LHRH and various stimulatory LHRH analogues are approximately equipotent in these fish. This is an unexpected result considering the superactive properties of these analogues demonstrated in mammals. An inhibitory LHRH analogue was also tested in the trout with the result that powerful inhibition of LHRH induced GtH release was obtained.

Original languageEnglish (US)
Pages (from-to)129-135
Number of pages7
JournalLife Sciences
Volume28
Issue number2
DOIs
StatePublished - Jan 12 1981
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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