Contrast manipulation in NMR imaging

W. H. Perman, S. K. Hilal, H. E. Simon, A. A. Maudsley

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


The past few years have shown rapid growth of NMR imaging in both image quality and diagnostic usefulness. It has become apparent, as the images have been published, that both inter- and intra-group imaging of the same underlying pathology produces images which can have vastly differing appearance. This effect is mainly due to imaging techniques which use different pulse sequence types and timings thus varying the relative contribution of the protpn density, T1, and T2 properties of the tissues. In this paper we investigate the contrast manipulation effects and methods for SNR optimization for the saturation recovery, inversion recovery, spin echo, and inversion recovery spin echo pulse sequences when applied to three clinically relevant imaging tasks.

Original languageEnglish (US)
Pages (from-to)23-32
Number of pages10
JournalMagnetic Resonance Imaging
Issue number1
StatePublished - 1984
Externally publishedYes


  • Contrast manipulation
  • Imaging
  • NMR
  • Signal-to-noise ratio

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics


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