Constitutive modeling of solute diffusivity in hydrated soft tissues

Wei Yong Gu, Hai Yao

Research output: Contribution to journalConference articlepeer-review


Based on the experimental results of electrical conductivity and hydraulic permeability, a new constitutive model for relative diffusivity (D/D o) of solutes in gels and tissues was developed. This model could predict the functional relationship between solute diffusivity and tissue deformation. This model could also quantitatively predict the effect of solute size on solute diffusivity in tissues. This study is important for the understanding of nutritional transport in cartilaginous tissues. It is also useful for the prediction of nutrition levels in tissue constructs during growth.

Original languageEnglish (US)
Article numberIMECE2004-59833
Pages (from-to)241-242
Number of pages2
JournalAdvances in Bioengineering, BED
StatePublished - 2004
Event2004 ASME International Mechanical Engineering Congress and Exposition, IMECE - Anaheim, CA, United States
Duration: Nov 13 2004Nov 19 2004

ASJC Scopus subject areas

  • Engineering(all)


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