Consensus statement from the 2014 International Microdialysis Forum

Peter J. Hutchinson, Ibrahim Jalloh, Adel Helmy, Keri L.H. Carpenter, Elham Rostami, Bo Michael Bellander, Martyn G. Boutelle, Jeff W. Chen, Jan Claassen, Claire Dahyot-Fizelier, Per Enblad, Clare N. Gallagher, Raimund Helbok, Lars Hillered, Peter D. Le Roux, Sandra Magnoni, Halinder S. Mangat, David K. Menon, Carl Henrik Nordström, Kristine H. O’PhelanMauro Oddo, Jon Perez Barcena, Claudia Robertson, Elisabeth Ronne-Engström, Juan Sahuquillo, Martin Smith, Nino Stocchetti, Antonio Belli, T. Adrian Carpenter, Jonathan P. Coles, Marek Czosnyka, Nil Dizdar, J. Clay Goodman, Arun K. Gupta, Troels H. Nielsen, Niklas Marklund, Ambroise Montcriol, Mark T. O’Connell, Maria A. Poca, Asita Sarrafzadeh, Richard J. Shannon, Jane Skjøth-Rasmussen, Peter Smielewski, John F. Stover, Ivan Timofeev, Paul Vespa, Elizabeth Zavala, Urban Ungerstedt

Research output: Contribution to journalArticlepeer-review

149 Scopus citations


Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has increased our understanding of the pathophysiology of several acute neurological disorders. In 2004, a consensus document on the clinical application of cerebral microdialysis was published. Since then, there have been significant advances in the clinical use of microdialysis in neurocritical care. The objective of this review is to report on the International Microdialysis Forum held in Cambridge, UK, in April 2014 and to produce a revised and updated consensus statement about its clinical use including technique, data interpretation, relationship with outcome, role in guiding therapy in neurocritical care and research applications.

Original languageEnglish (US)
Pages (from-to)1517-1528
Number of pages12
JournalIntensive Care Medicine
Issue number9
StatePublished - Sep 29 2015
Externally publishedYes


  • Brain chemistry
  • Microdialysis
  • Outcome
  • Subarachnoid hemorrhage
  • Traumatic brain injury

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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