Connective tissue nevi: A review of the literature

Harleen Arora, Leyre Falto-Aizpurua, Andrea Cortés-Fernandez, Sonal Choudhary, Paolo Romanelli

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Connective tissue nevi (CTN) are hamartomas of the dermis, with the 3 main components being collagen, elastin, and proteoglycans. Each subtype can present as a solitary lesion or multiple lesions. They could present as part of systemic diseases or inherited disorders. This article provides a comprehensive literature review of the different types of CTN, their clinical presentations, associations, and treatment options. Treatment options for 56 lesions were reviewed. Fifty-two percent of lesions were present in males, and the age range at the time of presentation was wide (1.6-80 years). Management varied according to CTN subtypes. Most lesions (14) received topical or intralesional treatment with corticosteroids, followed by surgical removal of lesions (12), whereas the remaining lesions were clinically monitored.

Original languageEnglish (US)
Pages (from-to)325-341
Number of pages17
JournalAmerican Journal of Dermatopathology
Volume39
Issue number5
DOIs
StatePublished - May 1 2017

Keywords

  • collagenoma
  • connective tissue nevi
  • elastoma
  • elastosis perforans serpiginosa
  • focal mucinosis
  • hunter's syndrome
  • lichen myxedematosus
  • pseudoxanthoma elasticum

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

Fingerprint Dive into the research topics of 'Connective tissue nevi: A review of the literature'. Together they form a unique fingerprint.

  • Cite this