Conjunctival cytology features of giant papillary conjunctivitis associated with ocular prostheses

Warren J. Chang, David Tse, Robert H. Rosa, Andrew Huang, Thomas Johnson, Joyce Schiffman

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Purpose: In this study, the conjunctival cytology features of giant papillary conjunctivitis (GPC) associated with ocular prosthesis wear was examined. Methods: In a prospective study, 12 consecutive patients diagnosed with GPC associated with ocular prosthesis wear were examined. Impression cytology specimens were taken from the upper eyelid tarsal conjunctiva, the bulbar conjunctiva, and the lower eyelid tarsal conjunctiva of each socket, with the contralateral eye serving as a matched control. Results: The randomized impression cytology specimens showed no significant change in goblet cell density or epithelial cell morphology when comparing the GPC and control specimens. The GPC specimens did have a statistically significant increase in conjunctival inflammation and mucous strands on all three sample areas. In addition, the GPC specimens from the upper and lower tarsal conjunctiva had a honeycomb pattern consistent with giant papillae. Conclusions: This is the first report to describe the honeycomb pattern created by giant papillae on impression cytology and the changes of GPC on the lower tarsal conjunctiva.

Original languageEnglish
Pages (from-to)39-45
Number of pages7
JournalOphthalmic Plastic and Reconstructive Surgery
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2005

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Artificial Eye
Allergic Conjunctivitis
Conjunctiva
Cell Biology
Eyelids
Goblet Cells
Cell Count
Epithelial Cells
Prospective Studies
Inflammation

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

Conjunctival cytology features of giant papillary conjunctivitis associated with ocular prostheses. / Chang, Warren J.; Tse, David; Rosa, Robert H.; Huang, Andrew; Johnson, Thomas; Schiffman, Joyce.

In: Ophthalmic Plastic and Reconstructive Surgery, Vol. 21, No. 1, 01.01.2005, p. 39-45.

Research output: Contribution to journalArticle

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