Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex

Robert E. Hampson, Joshua L. Fuqua, Peter F. Huettl, Ioan Opris, Dong Song, Dae Shin, Vasilis Z. Marmarelis, Theodore W. Berger, Greg A. Gerhardt, Sam A. Deadwyler

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Conformal ceramic electrodes utilized in prior recordings of nonhuman primate prefrontal cortical layer 2/3 and layer 5 neurons were used in this study to record tonic glutamate concentration and transient release in layer 2/3 PFC. Tonic glutamate concentration increased in the Match (decision) phase of a visual delayed-match-to-sample (DMS) task, while increased transient glutamate release occurred in the Sample (encoding) phase of the task. Further, spatial vs. object-oriented DMS trials evoked differential changes in glutamate concentration. Thus the same conformal recording electrodes were capable of electrophysiological and electrochemical recording, and revealed similar evidence of neural processing in layers 2/3 and layer 5 during cognitive processing in a behavioral task.

Original languageEnglish (US)
Title of host publication2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages5954-5957
Number of pages4
DOIs
StatePublished - Oct 31 2013
Externally publishedYes
Event2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
Duration: Jul 3 2013Jul 7 2013

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Other

Other2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
CountryJapan
CityOsaka
Period7/3/137/7/13

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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  • Cite this

    Hampson, R. E., Fuqua, J. L., Huettl, P. F., Opris, I., Song, D., Shin, D., Marmarelis, V. Z., Berger, T. W., Gerhardt, G. A., & Deadwyler, S. A. (2013). Conformal ceramic electrodes that record glutamate release and corresponding neural activity in primate prefrontal cortex. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 5954-5957). [6610908] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6610908