Conditional equivalence of chemical loading and mechanical loading on articular cartilage

W. Michael Lai, Weiyong Gu, Lori A. Setton, Van C. Mow

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

The objective of this paper is to ascertain the conditions for equivalence between chemical or osmotic loading and mechanical loading on articular cartilage. Constitutive equations for a charged-hydrated-soft tissue are given and chemical potentials are derived. Equivalence between chemical vs. mechanical load is discussed. Using the triphasic constitutive equations, it is shown that for every chemical load generated by a given concentration of polyethylene glycol (PEG) in a NaCl solution there corresponds an isotropic mechanical load, PA, which imparts to the tissue an identical equilibrium deformation. However, the mechanical load must be delivered in an isotropic manner via rigid-porous, free-draining loading platens.

Original languageEnglish (US)
Title of host publication1991 Advances in Bioengineering
PublisherPubl by ASME
Pages481-484
Number of pages4
ISBN (Print)0791808890
StatePublished - Dec 1 1991
Externally publishedYes
EventWinter Annual Meeting of the American Society of Mechanical Engineers - Atlanta, GA, USA
Duration: Dec 1 1991Dec 6 1991

Publication series

NameAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume20

Other

OtherWinter Annual Meeting of the American Society of Mechanical Engineers
CityAtlanta, GA, USA
Period12/1/9112/6/91

ASJC Scopus subject areas

  • Engineering(all)

Fingerprint Dive into the research topics of 'Conditional equivalence of chemical loading and mechanical loading on articular cartilage'. Together they form a unique fingerprint.

  • Cite this

    Lai, W. M., Gu, W., Setton, L. A., & Mow, V. C. (1991). Conditional equivalence of chemical loading and mechanical loading on articular cartilage. In 1991 Advances in Bioengineering (pp. 481-484). (American Society of Mechanical Engineers, Bioengineering Division (Publication) BED; Vol. 20). Publ by ASME.