The Co-Flow Jet (CFJ) flow control technology is promising to radically improve the takeoff/landing and cruise performance of aircraft due to its substantial lift augmentation and drag reduction performance with very low energy expenditure. A new promising technology in aircraft design is hybrid electric propulsion (HEP) technology, which integrates fuel engines and batteries to improve the energy efficiency and reduce CO2 emissions. The CFJ technology intrinsically employs distributed electric propulsion and is a desirable option for HEP. This paper investigates the potential benefits of Co-Flow jet (CFJ) hybrid electric propulsion (HEP) aircraft through a conceptual design of a regional airliner. The ATR72-500 regional airliner is chosen as a reference. The ATR72-500 aircraft has a range of 890 nm, a payload of 72 passengers and cruise Mach number of 0.46. The mission of the current CFJ hybrid electric regional airliner (CFJ-HERA) is to extend the range of ATR72-500. The CFJ-HERA uses an optimized CFJ wing configuration based on the CFJ6421-SST150-INJ117-SUC247 airfoil. Two different aspect ratios of 12 and 20 are studied for comparison. Both achieve substantially higher productivity efficiency than the baseline ATR72-500 airliner. With the same wing area as that of ATR72-500, the CFJ-HERA-AR12 design achieves a substantially longer range of 1960 nm and CFJ-HERA-AR20 further exceeds the range to 2850 nm. Due to the high lift cruise coefficient of CFJ wing, the CFJ-HERA has a wing loading of 660 kg/m2 and 746 kg/m2 for AR of 12 and 20 respectively. The significantly higher wing loading allows the airliners to carry much more fuel and batteries without increasing the wing size and weight, which results in the substantially longer range. The conceptual design of the CFJ-HERA indicates that the CFJ technology has a great potential to contribute the development of hybrid propulsion aircraft.