Concentrations of desipramine in elderly women

N. R. Cutler, A. P. Zavadil, C. Eisdorfer, R. J. Ross, W. Z. Potter

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Seven elderly depressed women were given desipramine, and plasma concentrations of the drug were measured from blood samples drawn after a single dose and during long-term use. The concentrations were no different from those found in younger patients. Aging does not seem to alter the plasma concentration of desipramine, and the authors conclude that the increased incidence and severity of the drug's side effects are probably not due to high drug concentrations.

Original languageEnglish (US)
Pages (from-to)1235-1237
Number of pages3
JournalUnknown Journal
Issue number9
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Psychiatry and Mental health


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