Computerized data analysis of amino acids in physiologic fluids

James H. Brown, Sherry Walker, Leah Casto, R. Rodney Howell

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.

Original languageEnglish (US)
Pages (from-to)293-304
Number of pages12
JournalJournal of Chromatography A
Volume116
Issue number2
DOIs
StatePublished - Jan 21 1976
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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