Abstract
A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.
| Original language | English |
|---|---|
| Pages (from-to) | 293-304 |
| Number of pages | 12 |
| Journal | Journal of Chromatography A |
| Volume | 116 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 21 1976 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Analytical Chemistry
Cite this
Computerized data analysis of amino acids in physiologic fluids. / Brown, James H.; Walker, Sherry; Casto, Leah; Howell, R.
In: Journal of Chromatography A, Vol. 116, No. 2, 21.01.1976, p. 293-304.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Computerized data analysis of amino acids in physiologic fluids
AU - Brown, James H.
AU - Walker, Sherry
AU - Casto, Leah
AU - Howell, R.
PY - 1976/1/21
Y1 - 1976/1/21
N2 - A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.
AB - A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.
UR - http://www.scopus.com/inward/record.url?scp=0017312383&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017312383&partnerID=8YFLogxK
U2 - 10.1016/S0021-9673(00)89900-8
DO - 10.1016/S0021-9673(00)89900-8
M3 - Article
VL - 116
SP - 293
EP - 304
JO - Journal of Chromatography
JF - Journal of Chromatography
SN - 0021-9673
IS - 2
ER -