Computerized data analysis of amino acids in physiologic fluids

James H. Brown; Sherry Walker; Leah Casto; R. Rodney Howell

doi:10.1016/S0021-9673(00)89900-8

Computerized data analysis of amino acids in physiologic fluids

James H. Brown, Sherry Walker, Leah Casto, R. Rodney Howell

Research output: Contribution to journal › Article

4 Scopus citations

Abstract

A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.

Original language	English (US)
Pages (from-to)	293-304
Number of pages	12
Journal	Journal of Chromatography A
Volume	116
Issue number	2
DOIs	https://doi.org/10.1016/S0021-9673(00)89900-8
State	Published - Jan 21 1976
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Organic Chemistry

Access to Document

10.1016/S0021-9673(00)89900-8

Fingerprint Dive into the research topics of 'Computerized data analysis of amino acids in physiologic fluids'. Together they form a unique fingerprint.

Cite this

Brown, J. H., Walker, S., Casto, L., & Howell, R. R. (1976). Computerized data analysis of amino acids in physiologic fluids. Journal of Chromatography A, 116(2), 293-304. https://doi.org/10.1016/S0021-9673(00)89900-8

@article{a71db88152c54fb689a9f49c64b8a1d5,

title = "Computerized data analysis of amino acids in physiologic fluids",

abstract = "A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.",

author = "Brown, {James H.} and Sherry Walker and Leah Casto and Howell, {R. Rodney}",

year = "1976",

month = jan,

day = "21",

doi = "10.1016/S0021-9673(00)89900-8",

language = "English (US)",

volume = "116",

pages = "293--304",

journal = "Journal of Chromatography A",

issn = "0021-9673",

number = "2",

}

TY - JOUR

T1 - Computerized data analysis of amino acids in physiologic fluids

AU - Brown, James H.

AU - Walker, Sherry

AU - Casto, Leah

AU - Howell, R. Rodney

PY - 1976/1/21

Y1 - 1976/1/21

N2 - A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.

AB - A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.

UR - http://www.scopus.com/inward/record.url?scp=0017312383&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017312383&partnerID=8YFLogxK

U2 - 10.1016/S0021-9673(00)89900-8

DO - 10.1016/S0021-9673(00)89900-8

M3 - Article

C2 - 1245574

AN - SCOPUS:0017312383

VL - 116

SP - 293

EP - 304

JO - Journal of Chromatography A

JF - Journal of Chromatography A

SN - 0021-9673

IS - 2

ER -