Computerized data analysis of amino acids in physiologic fluids

James H. Brown, Sherry Walker, Leah Casto, R. Howell

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A Fortran IV computer program is described which identifies, computes, and statistically evaluates amino acid concentrations determined by an automatic amino acid analyzer in physiologic fluids. The program accepts retention time and integrated peak areas from two calibration standards for identification and computational reference. Two internal standards are used to compensate for variations in injector performance and ninhydrin decay. Calibration standard responses are statistically treated to assist in detection of equipment malfunction. The statistical data base is automatically expanded through inclusion of data from normal patients. Amino acid concentrations are printed with appropriate mean and standard deviation values in a format acceptable as a final report.

Original languageEnglish
Pages (from-to)293-304
Number of pages12
JournalJournal of Chromatography A
Volume116
Issue number2
DOIs
StatePublished - Jan 21 1976
Externally publishedYes

Fingerprint

Amino Acids
Calibration
Fluids
Equipment Failure
Ninhydrin
Computer program listings
Software
Databases

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Computerized data analysis of amino acids in physiologic fluids. / Brown, James H.; Walker, Sherry; Casto, Leah; Howell, R.

In: Journal of Chromatography A, Vol. 116, No. 2, 21.01.1976, p. 293-304.

Research output: Contribution to journalArticle

Brown, James H. ; Walker, Sherry ; Casto, Leah ; Howell, R. / Computerized data analysis of amino acids in physiologic fluids. In: Journal of Chromatography A. 1976 ; Vol. 116, No. 2. pp. 293-304.
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