TY - JOUR
T1 - Comprehensive long-term management program for asthma
T2 - Effect on outcomes in adult African-Americans
AU - Kelso, Tiffany M.
AU - Abou-Shala, Nabil
AU - Heilker, Greta M.
AU - Arheart, Kristopher L.
AU - Portner, Tracy S.
AU - Self, Timothy H.
N1 - Funding Information:
Supported in part by an investigator-initiated grant from Glaxo Wellcome Inc. and by a grant (M01-RR002211) from General Clinic Research Center.
PY - 1996/6
Y1 - 1996/6
N2 - To determine if a comprehensive long-term management program, emphasizing inhaled corticosteroids and patient education, would improve outcomes in adult African-American asthmatics a nonrandomized control trial with a 2- year intervention was performed in a university-based clinic. Inclusion criteria consisted of (≥5) emergency department (ED) visits or hospitalizations (≥2) during the previous 2 years. Intervention patients were volunteers; a comparable control group was identified via chart review at hospitals within the same area and time period as the intervention patients. Individualized doses of beclomethasone with a spacer, inhaled albuterol 'as needed,' and crisis prednisone were the primary therapies. Environmental control, peak flow monitoring, and a partnership with the patient were emphasized. Detailed patient education was an integral part of management. Control patients received usual care from local physicians. ED visits and hospitalizations for 2 years before and 2 years during the intervention period were compared. Quality of life (QOL) measurements were made at baseline and every 6 months in the intervention group. Study group (n = 21) had a significant reduction in ED visits (2.3 ± 0.2 pre-intervention versus 0.6 ± 0.2 post-intervention; P = 0.0001). Control group (n = 18) did not have a significant change in ED visits during the 2-year post- intervention period (2.6 ± 0.2 pre-intervention versus 2.0 ± 0.2 post- intervention; P = 0.11). Both groups had significant reductions in hospitalizations, but the study group had a greater reduction. Sixty-two percent of study patients had complete elimination of ED visits and hospitalizations, whereas no control patients had total elimination of the need for institutional acute care. QOL in the study patients revealed significant improvements for most parameters. A comprehensive long-term management program emphasizing inhaled corticosteroids combined with other state-of-the-art management, including intensive patient education, improves outcomes in adult African-American asthmatics.
AB - To determine if a comprehensive long-term management program, emphasizing inhaled corticosteroids and patient education, would improve outcomes in adult African-American asthmatics a nonrandomized control trial with a 2- year intervention was performed in a university-based clinic. Inclusion criteria consisted of (≥5) emergency department (ED) visits or hospitalizations (≥2) during the previous 2 years. Intervention patients were volunteers; a comparable control group was identified via chart review at hospitals within the same area and time period as the intervention patients. Individualized doses of beclomethasone with a spacer, inhaled albuterol 'as needed,' and crisis prednisone were the primary therapies. Environmental control, peak flow monitoring, and a partnership with the patient were emphasized. Detailed patient education was an integral part of management. Control patients received usual care from local physicians. ED visits and hospitalizations for 2 years before and 2 years during the intervention period were compared. Quality of life (QOL) measurements were made at baseline and every 6 months in the intervention group. Study group (n = 21) had a significant reduction in ED visits (2.3 ± 0.2 pre-intervention versus 0.6 ± 0.2 post-intervention; P = 0.0001). Control group (n = 18) did not have a significant change in ED visits during the 2-year post- intervention period (2.6 ± 0.2 pre-intervention versus 2.0 ± 0.2 post- intervention; P = 0.11). Both groups had significant reductions in hospitalizations, but the study group had a greater reduction. Sixty-two percent of study patients had complete elimination of ED visits and hospitalizations, whereas no control patients had total elimination of the need for institutional acute care. QOL in the study patients revealed significant improvements for most parameters. A comprehensive long-term management program emphasizing inhaled corticosteroids combined with other state-of-the-art management, including intensive patient education, improves outcomes in adult African-American asthmatics.
KW - Asthma
KW - Inhaled corticosteroids
KW - Minorities
KW - Outcomes
KW - Patient education
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U2 - 10.1097/00000441-199606000-00009
DO - 10.1097/00000441-199606000-00009
M3 - Article
C2 - 8659554
AN - SCOPUS:0030014752
VL - 311
SP - 272
EP - 280
JO - American Journal of the Medical Sciences
JF - American Journal of the Medical Sciences
SN - 0002-9629
IS - 6
ER -