Comprehensive evaluation of left hemisphere type I schizencephaly

Bonnie Levin, B. E. Levin, R. E. Ramsay, Howard Landy

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We report the neuropsychological, magnetic resonance imaging, electroencephalographic telemetry, and sodium amytal test findings of a 32- year-old, left-handed man with unilateral left hemisphere type I schizencephaly. The patient was referred for treatment of medically refractory left temporal complex partial seizures that developed at age 26 years. Sodium amytal testing revealed complete incorporation of speech and language function by the right hemisphere. Detailed neuropsychological evaluation indicated average to above-average performance on all measures of language skills, judgment and reasoning, visuospatial abilities, and memory function. This case demonstrates that extensive but lateralized neuronal migration disorders can be associated with complete reorganization and full recovery of function by the contralateral hemisphere. Furthermore, this case supports the view that the degree of recovery is greatest when compensatory mechanisms are activated antenatally.

Original languageEnglish
Pages (from-to)667-669
Number of pages3
JournalArchives of Neurology
Volume50
Issue number6
StatePublished - Jan 1 1993

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Amobarbital
Language
Group II Malformations of Cortical Development
Telemetry
Aptitude
Recovery of Function
Seizures
Magnetic Resonance Imaging
Schizencephaly
Evaluation
Recovery
Left Hemisphere
Therapeutics
Hemisphere
Functions of Language
Right Hemisphere
Reorganization
Testing
Language Skills

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Comprehensive evaluation of left hemisphere type I schizencephaly. / Levin, Bonnie; Levin, B. E.; Ramsay, R. E.; Landy, Howard.

In: Archives of Neurology, Vol. 50, No. 6, 01.01.1993, p. 667-669.

Research output: Contribution to journalArticle

Levin, Bonnie ; Levin, B. E. ; Ramsay, R. E. ; Landy, Howard. / Comprehensive evaluation of left hemisphere type I schizencephaly. In: Archives of Neurology. 1993 ; Vol. 50, No. 6. pp. 667-669.
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