Complications of transvenous right ventricular endomyocardial biopsy in adult patients with cardiomyopathy

A seven-year survey of 546 consecutive diagnostic procedures in a tertiary referral center

Jaap W. Deckers, Joshua Hare, Kenneth L. Baughman

Research output: Contribution to journalArticle

162 Citations (Scopus)

Abstract

To determine the incidence, nature and subsequent management of complications occurring during right ventricular endomyocardial biopsy in patients with cardiomyopathy, all events occurring during 546 procedures in 464 consecutive patients were prospectively recorded. The internal jugular vein was the primary site of introduction in 96% of cases. A total of 33 complications (6%) occurred: 15 (2.7%) during catheter insertion including 12 arterial punctures (2%), 2 vasovagal reactions (0.4%) and 1 episode of prolonged bleeding (0.2%), all without sequelae; 18 (3.3%) during biopsy included 6 arrhythmias (1.1%), 5 conduction abnormalities (1%), 4 possible perforations (0.7%) and 3 definite perforations (0.5%) (pericardial fluid). Two (0.4%) of the three patients with a perforation died. There was no secular trend in the complication rate, nor were complications associated with specific clinical or hemodynamic characteristics. It is concluded that the overall rate of endomyocardial biopsy complications (6%) is low, but mortality may occur.

Original languageEnglish
Pages (from-to)43-47
Number of pages5
JournalJournal of the American College of Cardiology
Volume19
Issue number1
DOIs
StatePublished - Jan 1 1992
Externally publishedYes

Fingerprint

Cardiomyopathies
Tertiary Care Centers
Biopsy
Jugular Veins
Punctures
Cardiac Arrhythmias
Catheters
Hemodynamics
Hemorrhage
Mortality
Incidence
Surveys and Questionnaires

ASJC Scopus subject areas

  • Nursing(all)

Cite this

@article{812053f109e3404399ac92aef9683897,
title = "Complications of transvenous right ventricular endomyocardial biopsy in adult patients with cardiomyopathy: A seven-year survey of 546 consecutive diagnostic procedures in a tertiary referral center",
abstract = "To determine the incidence, nature and subsequent management of complications occurring during right ventricular endomyocardial biopsy in patients with cardiomyopathy, all events occurring during 546 procedures in 464 consecutive patients were prospectively recorded. The internal jugular vein was the primary site of introduction in 96{\%} of cases. A total of 33 complications (6{\%}) occurred: 15 (2.7{\%}) during catheter insertion including 12 arterial punctures (2{\%}), 2 vasovagal reactions (0.4{\%}) and 1 episode of prolonged bleeding (0.2{\%}), all without sequelae; 18 (3.3{\%}) during biopsy included 6 arrhythmias (1.1{\%}), 5 conduction abnormalities (1{\%}), 4 possible perforations (0.7{\%}) and 3 definite perforations (0.5{\%}) (pericardial fluid). Two (0.4{\%}) of the three patients with a perforation died. There was no secular trend in the complication rate, nor were complications associated with specific clinical or hemodynamic characteristics. It is concluded that the overall rate of endomyocardial biopsy complications (6{\%}) is low, but mortality may occur.",
author = "Deckers, {Jaap W.} and Joshua Hare and Baughman, {Kenneth L.}",
year = "1992",
month = "1",
day = "1",
doi = "10.1016/0735-1097(92)90049-S",
language = "English",
volume = "19",
pages = "43--47",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Elsevier USA",
number = "1",

}

TY - JOUR

T1 - Complications of transvenous right ventricular endomyocardial biopsy in adult patients with cardiomyopathy

T2 - A seven-year survey of 546 consecutive diagnostic procedures in a tertiary referral center

AU - Deckers, Jaap W.

AU - Hare, Joshua

AU - Baughman, Kenneth L.

PY - 1992/1/1

Y1 - 1992/1/1

N2 - To determine the incidence, nature and subsequent management of complications occurring during right ventricular endomyocardial biopsy in patients with cardiomyopathy, all events occurring during 546 procedures in 464 consecutive patients were prospectively recorded. The internal jugular vein was the primary site of introduction in 96% of cases. A total of 33 complications (6%) occurred: 15 (2.7%) during catheter insertion including 12 arterial punctures (2%), 2 vasovagal reactions (0.4%) and 1 episode of prolonged bleeding (0.2%), all without sequelae; 18 (3.3%) during biopsy included 6 arrhythmias (1.1%), 5 conduction abnormalities (1%), 4 possible perforations (0.7%) and 3 definite perforations (0.5%) (pericardial fluid). Two (0.4%) of the three patients with a perforation died. There was no secular trend in the complication rate, nor were complications associated with specific clinical or hemodynamic characteristics. It is concluded that the overall rate of endomyocardial biopsy complications (6%) is low, but mortality may occur.

AB - To determine the incidence, nature and subsequent management of complications occurring during right ventricular endomyocardial biopsy in patients with cardiomyopathy, all events occurring during 546 procedures in 464 consecutive patients were prospectively recorded. The internal jugular vein was the primary site of introduction in 96% of cases. A total of 33 complications (6%) occurred: 15 (2.7%) during catheter insertion including 12 arterial punctures (2%), 2 vasovagal reactions (0.4%) and 1 episode of prolonged bleeding (0.2%), all without sequelae; 18 (3.3%) during biopsy included 6 arrhythmias (1.1%), 5 conduction abnormalities (1%), 4 possible perforations (0.7%) and 3 definite perforations (0.5%) (pericardial fluid). Two (0.4%) of the three patients with a perforation died. There was no secular trend in the complication rate, nor were complications associated with specific clinical or hemodynamic characteristics. It is concluded that the overall rate of endomyocardial biopsy complications (6%) is low, but mortality may occur.

UR - http://www.scopus.com/inward/record.url?scp=0026592734&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026592734&partnerID=8YFLogxK

U2 - 10.1016/0735-1097(92)90049-S

DO - 10.1016/0735-1097(92)90049-S

M3 - Article

VL - 19

SP - 43

EP - 47

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

SN - 0735-1097

IS - 1

ER -