Complications and functional results after limb-salvage surgery and radiotherapy for difficult mesenchymal neoplasms: A prospective analysis

R. S. Bell, B. O'Sullivan, F. Langer, J. L. Mahoney, S. V. Lichtenstein, Frederick L Moffat, B. J. Cummings, N. V. Hawkins, V. L. Fornasier

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Wild resection with adjuvant radiotherapy is generally accepted as the optimal treatment for patients with extremity soft-tissue sarcomas. However, there is a subset of patients with 'difficult' tumours who sustain such marked loss of function from limb-salvage procedures that amputation might offer a superior functional alternative. To evaluate this issue, the authors prospectively designated 19 of 52 patients registered in Toronto's Princess Margaret Hospital Prospective Sarcoma Database in 1986 as 'difficult' cases, on the basis of tumour size and anatomical location. Complications and functional results of wide resection and adjuvant radiotherapy were documented. The most frequent complication was related to wound healing (8 of 19 patients). Functional analysis at 1 year follow-up demonstrated that all 19 patients had results superior to those that would be expected with amputation.

Original languageEnglish
Pages (from-to)69-73
Number of pages5
JournalCanadian Journal of Surgery
Volume32
Issue number1
StatePublished - Jan 1 1989
Externally publishedYes

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Limb Salvage
Radiotherapy
Adjuvant Radiotherapy
Neoplasms
Amputation
Sarcoma
Wound Healing
Extremities
Databases

ASJC Scopus subject areas

  • Surgery

Cite this

Bell, R. S., O'Sullivan, B., Langer, F., Mahoney, J. L., Lichtenstein, S. V., Moffat, F. L., ... Fornasier, V. L. (1989). Complications and functional results after limb-salvage surgery and radiotherapy for difficult mesenchymal neoplasms: A prospective analysis. Canadian Journal of Surgery, 32(1), 69-73.

Complications and functional results after limb-salvage surgery and radiotherapy for difficult mesenchymal neoplasms : A prospective analysis. / Bell, R. S.; O'Sullivan, B.; Langer, F.; Mahoney, J. L.; Lichtenstein, S. V.; Moffat, Frederick L; Cummings, B. J.; Hawkins, N. V.; Fornasier, V. L.

In: Canadian Journal of Surgery, Vol. 32, No. 1, 01.01.1989, p. 69-73.

Research output: Contribution to journalArticle

Bell, RS, O'Sullivan, B, Langer, F, Mahoney, JL, Lichtenstein, SV, Moffat, FL, Cummings, BJ, Hawkins, NV & Fornasier, VL 1989, 'Complications and functional results after limb-salvage surgery and radiotherapy for difficult mesenchymal neoplasms: A prospective analysis', Canadian Journal of Surgery, vol. 32, no. 1, pp. 69-73.
Bell, R. S. ; O'Sullivan, B. ; Langer, F. ; Mahoney, J. L. ; Lichtenstein, S. V. ; Moffat, Frederick L ; Cummings, B. J. ; Hawkins, N. V. ; Fornasier, V. L. / Complications and functional results after limb-salvage surgery and radiotherapy for difficult mesenchymal neoplasms : A prospective analysis. In: Canadian Journal of Surgery. 1989 ; Vol. 32, No. 1. pp. 69-73.
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