Complex partial seizures in infancy and childhood

M. S. Duchowny

Research output: Contribution to journalArticlepeer-review


Complex partial seizures (CPS) are relatively frequent in early childhood and have clinical and electrophysiologic features which distinguish them from adult CPS and other forms of childhood epilepsy. Motionless staring, tonic and clonic movements and automatisms are frequent seizure manifestations whereas psychosensory disturbances are uncommon. Approximately 50% of patients can be controlled by pharmacologic agents including carbamazepine, phenytoin, phenobarbital and valproate. Children whose seizures remain uncontrolled are at considerable risk for later psychosocial disturbances. A high proportion of intractable CPS results from structural lesions such as mesial temporal sclerosis, congenital alien tissue or indolent tumors. Excisional surgery offers a 60-70% chance for permanent seizure remission and restoration of normal behavior functioning. The indications for surgery are clear by puberty and referral to a tertiary epilepsy center should be made as early as possible.

Original languageEnglish (US)
Pages (from-to)193-200
Number of pages8
JournalInternational Pediatrics
Issue number2
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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